A study looking for circulating tumour cells from neuroblastoma

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Children's cancers





This study is looking at collecting tumour cells that have broken away from neuroblastoma and are circulating in the blood.

This trial is for children and people up to and including the age of 40. We use the term 'you' in this summary, but of course if you are a parent, we are referring to your child.


More about this trial

Neuroblastoma is a rare cancer that usually develops in children under the age of 5 years old.

It is possible that small parts of the neuroblastoma break away, travel in the bloodstream and spread to other parts of the body including the bone marrow Open a glossary item. These cells are called circulating tumour cells (CTCs).

The researchers want to find out if it is possible to collect these circulating tumour cells from samples of your blood and bone marrow. If they are able to do this, they also want to try and use these cells to develop new drugs to treat neuroblastoma.

Who can enter

You may be able to join this study if all of the following apply. You

You cannot join this study if any of these apply. You

  • Are under 10 kgs
  • Are older than 40 when you are first diagnosed

Trial design

This is a pilot study. The study team needs 40 people to join.

When you give your routine blood samples and bone marrow sample, the study team will ask for a little extra blood and bone marrow to be taken for the study.

Hospital visits

There are no extra hospital visits if you take part in this study.

Side effects

You may have some bruising or bleeding from where you have the blood sample taken.

Having a bone marrow sample taken is a safe procedure. You may have a small amount of bleeding from the site where the needle went in. You will have a dressing over the site which you should keep on for about 24 hours. If you notice any bleeding apply pressure to the area. If it doesn't stop contact the hospital.

We have information about having a bone marrow test.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Deborah Tweddle

Supported by

Cancer Research UK
NIHR Clinical Research Network: Cancer
Newcastle Healthcare Charity
The Newcastle upon Tyne Hospitals NHS Foundation Trust

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Around 1 in 5 people take part in clinical trials

3 phases of trials

Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.

Last reviewed:

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