A study looking at setting up a trial of chemotherapy for frail and elderly patients with advanced cancer of the food pipe (oesophagus) and stomach (321GO)

This study looked at the possibility of setting up a large phase 3 trial of chemotherapy for frail and elderly patients. It was for people with advanced cancer of the oesophagus, stomach, or the area where the stomach and oesophagus meet (the gastro oesophageal junction). This study was supported by Cancer Research UK.

Doctors often treat advanced cancer with chemotherapy. But some people are older and not well enough to have full strength chemotherapy. Sometimes doctors give these patients less chemotherapy. But the research team felt that we needed more evidence to decide which treatment option is best.

The aim of this study was to find out if it is practical to do a phase 3 trial testing three types of chemotherapy for frail and elderly patients with advanced oesophageal or stomach cancer.