Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study looking at proteins called CTCF and BORIS as possible biomarkers for breast and prostate cancer
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This study is looking at proteins called CTCF and BORIS in blood and samples of tissue removed during surgery.
Researchers are looking for substances in the body that can help them to diagnose cancer, and to work out how well people are likely to respond to treatment. These substances are called
In this study, they are trying to find out how useful proteins called CTCF and BORIS would be as biomarkers for breast cancer and prostate cancer. The researchers will study blood samples from people with breast or prostate cancer and also samples of breast or prostate tissue removed during surgery.
They want to look at samples from people who are diagnosed with cancer, as well as samples from people who do not have cancer. So being asked to take part in this study does not mean you have cancer.
Please note - you won’t get any direct benefit from taking part in the study, nor will it affect any treatment you may need to have. It is possible that the findings may help people in the future.
Who can enter
You can enter this trial if you are a man having prostate surgery or a woman having breast surgery at Colchester General Hospital or Essex County Hospital. People are usually invited to join this trial, but you can also volunteer.
The study team will keep some of the tissue removed when you have surgery. They will also take a small blood sample. They will use these samples to study proteins called CTCF and BORIS.
Taking part in the study does not involve having any extra tissue removed. Your surgeon will only remove the necessary amount of tissue to make a diagnosis and see if you need to have treatment. The researchers will keep the tissue that is left over after all other tests you need have been done.
The samples will be anonymous, so the researchers will not know who you are. And they will not know any of your personal or medical details. The samples will not be used for anything other than this study and they will be destroyed after 5 years.
Taking part in this study does not involve any extra hospital visits.
There are no side effects associated with taking part in the study.
How to join a clinical trial
Association for International Cancer Research (AICR)
Breast Cancer Campaign
Cancer Research UK
Colchester Hospital University NHS Foundation Trust
NIHR Clinical Research Network: Cancer
University of Essex