A study looking at a way to report side effects of treatment online from home (eRAPID RCT)

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Bowel (colorectal) cancer
Breast cancer
Cervical cancer
Ovarian cancer
Vaginal cancer
Vulval cancer
Womb (uterine or endometrial) cancer





This study is looking at using a computer based system for people to report treatment side effects on line. Systemic treatment Open a glossary item such as chemotherapy causes side effects.

Researchers want to find out how useful people having systemic treatment and health professionals find the on line system. They want to see if there are benefits to using this system in comparison with the care people would usually receive.

More about this trial

eRAPID is an online system for people to report their symptoms and side effects during and after cancer treatment. It has already been tested in a study with a small number of people. The researchers now want to test the system with a larger group of people who are having systemic treatment for one of the following cancers

Who can enter

You may be able to join this study if all of the following apply. You

You cannot join this study if any of these apply. You

  • Are taking part in another clinical trial which includes frequent quality of life study studies
  • Have problems with your memory or concentration, or have a mental health problem
  • Have taken part in a previous eRAPID study

Trial design

This study is taking place at St James Hospital in Leeds. The researchers need up to 588 people to take part. The study is randomised. Everyone taking part is put into 1 of 2 groups by a computer. Neither you nor your doctor will be able to decide which group you are in.

People in one group will have usual care during the time they have their treatment. People in the other group will be trained and asked to use the eRAPID symptom questionnaire routinely from home during treatment. This will be in addition to usual care.

If you are in the group using the eRAPID system, a researcher will show you how to complete the online questionnaires. They will give you details of how you log in to the system and a booklet that explains how to use it. They will ask you to log in to the eRAPID system at least once a week during your treatment. You can do this at home.

A friend or relative can help you to use the system, but the researchers would like you to answer the questionnaire yourself. It might also be possible to use the system at the hospital before you have an appointment. Your doctor will be able to look at your answers to the questionnaire and will go through the information either when they see you in clinic or by telephone.

Everyone will be asked to complete some other questionnaires at certain times during the study. These questionnaires will cover your views of your health and treatment, and your quality of life. The researchers are also interested in the financial impact of cancer and so the questionnaires will cover this too.

The study team will also look at your medical notes so they can see how often you had to contact either the hospital or your GP during the time you had treatment.

Hospital visits

If you take part in this study there are no additional hospital visits outside of those for your cancer treatment.

Side effects

There are no side effects associated with this study.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Galina Velikova

Supported by

NIHR Clinical Research Network: Cancer
The Leeds Teaching Hospitals NHS Trust
University of Leeds

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Around 1 in 5 people take part in clinical trials

3 phases of trials

Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.

Last reviewed:

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