Acute lymphoblastic leukaemia (ALL) incidence statistics

Coronavirus (COVID-19)

We have created a central resources hub for Health Professionals which hosts all of our CRUK resources and further materials to help with managing the pandemic. We are updating the information as guidance changes. There is also a page specifically for patients on our about cancer hub.

Health Professional COVID-19 and Cancer Hub

Cases

New cases of acute lymphoblastic leukaemia, 2015-2017, UK.

 

Proportion of all cases

Percentage acute lymphoblastic leukaemia is of total cancer cases, 2015-2017, UK

 

Age

Peak rate of acute lymphoblastic leukaemia cases, 2015-2017, UK

 

Trend over time

Acute lymphoblastic leukaemia incidence rates have remained stable since the early 1990s, UK

 

Acute lymphoblastic leukaemia accounted for less than 1% of all new cancer cases in the UK in 2017.[1-4]

In females in the UK, acute lymphoblastic leukaemia accounted for less than 1% of all new female cancer cases. In males in the UK, it accounted for less than 1% of all new male cancer cases).

42% of acute lymphoblastic leukaemia cases in the UK are in females, and 58% are in males.

Acute lymphoblastic leukaemia incidence rates (European age-standardised (AS) rates Open a glossary item) for persons are similar to the UK average in all the UK constituent countries.

Acute Lymphoblastic Leukaemia (C91.0), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2017

  England Scotland Wales Northern Ireland UK
Female Cases 283 28 9 10 330
Crude Rate 1.0 1.0 0.6 1.1 1.0
AS Rate 1.0 1.0 0.6 1.0 0.9
AS Rate - 95% LCL 0.8 0.6 0.2 0.4 0.8
AS Rate - 95% UCL 1.1 1.4 0.9 1.6 1.0
Male Cases 383 35 16 17 451
Crude Rate 1.4 1.3 1.0 1.8 1.4
AS Rate 1.3 1.3 1.0 1.6 1.3
AS Rate - 95% LCL 1.2 0.8 0.5 0.8 1.2
AS Rate - 95% UCL 1.4 1.7 1.5 2.4 1.4
Persons Cases 666 63 25 27 781
Crude Rate 1.2 1.2 0.8 1.4 1.2
AS Rate 1.1 1.1 0.8 1.3 1.1
AS Rate - 95% LCL 1.0 0.9 0.5 0.8 1.0
AS Rate - 95% UCL 1.2 1.4 1.1 1.8 1.2

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate Open a glossary item

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, November 2019. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, December 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2019. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2017, ICD-10 C91.0.

Last reviewed:

Acute lymphoblastic leukaemia incidence is strongly related to age, with the highest incidence rates being in the 0 to 04 age group. In the UK in 2015-2017, on average each year around 5 in 100 new cases (6%) were in people aged 75 and over.[1-4] In contrast to most cancer types, acute lymphoblastic leukaemia occurs most frequently at younger ages.

Age-specific incidence rates are highest in infants aged 0-4 and drop sharply through childhood, adolescence and young adulthood, reaching their lowest point at age 35-39, and increasing slightly thereafter.The highest rates are in in the 0 to 04 age group for females and males.

Incidence rates are significantly lower in females than males in a number of (mainly younger) age groups.The gap is widest at age 30 to 34, when the age-specific incidence rate is 2.9 times lower in females than males.

Acute lymphoblastic leukaemia (C91.0), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Population, UK, 2015-2017

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, November 2019. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, December 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2019. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2015-2017, C91.0.

Last reviewed:

Acute lymphoblastic leukaemia European age-standardised (AS) Open a glossary item incidence rates for females and males combined remained stable in the UK between 1993-1995 and 2015-2017.[1-4] The rate remained stable in both females and males.

For females, acute lymphoblastic leukaemia AS incidence rates in the UK remained stable between 1993-1995 and 2015-2017. For males, acute lymphoblastic leukaemia AS incidence rates in the UK remained stable between 1993-1995 and 2015-2017.

Over the last decade in the UK (between 2005-2007 and 2015-2017), acute lymphoblastic leukaemia AS incidence rates for females and males combined remained stable. In females AS incidence rates remained stable, and in males rates remained stable.

Acute Lymphoblastic Leukaemia (ICD-10 C91.0), European Age-Standardised Incidence Rates, UK, 1993-2017

Acute lymphoblastic leukaemia incidence rates have remained stable overall in most broad age groups in females and males combined in the UK since the early 1990s, but have decreased in some.[1-4] Rates in 0-24s have remained stable, in 25-49s have remained stable, in 50-59s have remained stable, in 60-69s have remained stable, in 70-79s have remained stable, and in 80+s have decreased by 46%.

Acute Lymphoblastic Leukaemia (ICD-10 C91.0), European Age-Standardised Incidence Rates, By Age, UK, 1993-2017

For acute lymphoblastic leukaemia there are few established risk factors, therefore increasing incidence in the 1980s and 1990s may largely reflect improvements in diagnosis and data recording.

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, November 2019. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, December 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, May 2019. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1993-2017, ICD-10 C91.0.

Last reviewed:

Acute lymphoblastic leukaemia incidence rates (European age-standardised (AS) rates Open a glossary item) in England in females are similar in the most deprived quintile compared with the least, and in males are similar in the most deprived quintile compared with the least (2013-2017).[1]

References

  1. Calculated by the Cancer Intelligence Team at Cancer Research UK, April 2020. Based on method reported in National Cancer Intelligence Network Cancer by Deprivation in England Incidence, 1996-2010 Mortality, 1997-2011 . Using cancer incidence data 2013-2017 (Public Health England) and population data 2013-2017 (Office for National Statistics) by Indices of Multiple Deprivation 2015 income domain quintile, cancer type, sex, and five-year age band.

About this data

Data is for England, 2013-2017, ICD-10 C21.

Last reviewed:

An estimated 8,200 people who had been diagnosed with acute lymphoblastic leukaemia (ALL) between 1991 and 2010 were alive in the UK at the end of 2010.[1]

References

  1. Macmillan Cancer Support and National Cancer Registration and Analysis Service. Cancer Prevalence UK Data Tables. London: NCRAS; 2015.

About this data

Data is for: Great Britain (1991 and 2010) and Northern Ireland (1993-2010), ICD-10 C91.0.

Last reviewed:

Cancer stats explained

See information and explanations on terminology used for statistics and reporting of cancer, and the methods used to calculate some of our statistics.

Citation

You are welcome to reuse this Cancer Research UK content for your own work.
Credit us as authors by referencing Cancer Research UK as the primary source. Suggested styles are:

Web content: Cancer Research UK, full URL of the page, Accessed [month] [year].
Publications: Cancer Research UK ([year of publication]), Name of publication, Cancer Research UK.
Graphics (when reused unaltered): Credit: Cancer Research UK.
Graphics (when recreated with differences): Based on a graphic created by Cancer Research UK.

When Cancer Research UK material is used for commercial reasons, we encourage a donation to our life-saving research.
Send a cheque payable to Cancer Research UK to: Cancer Research UK, 2 Redman Place, London, E20 1JQ or

Donate online

Join the conversation and follow @CRUKHCPs for news, updates and opinion.

@CRUKHCPs

Acknowledgements

We are grateful to the many organisations across the UK which collect, analyse, and share the data which we use, and to the patients and public who consent for their data to be used. Find out more about the sources which are essential for our statistics.