Acute lymphoblastic leukaemia (ALL) mortality statistics

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Deaths

Deaths from acute lymphoblastic leukaemia, 2016-2018, UK.

Proportion of all deaths

Percentage acute lymphoblastic leukaemia contributes to total cancer deaths, 2016-2018, UK

Age

Peak mortality rate for acute lymphoblastic leukaemia, 2016-2018, UK

Trend over time

Change in acute lymphoblastic leukaemia mortality rates since the early 1970s, UK

Acute lymphoblastic leukaemia accounted for less than 1% of all cancer deaths in the UK in 2018.[1-3]

In females in the UK, acute lymphoblastic leukaemia accounted for less than 1% of all female cancer deaths. In males in the UK, it accounted for less than 1% of all male cancer deaths).

44% of acute lymphoblastic leukaemia deaths in the UK are in females, and 56% are in males (2018).

Acute lymphoblastic leukaemia mortality rates (European age-standardised (AS Open a glossary item) rates) are similar to the UK average in all the UK constituent countries.

For acute lymphoblastic leukaemia mortality and incidence rates do not vary between the UK constituent nations.

Acute Lymphoblastic Leukaemia (C91.0), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2018

  England Scotland Wales Northern Ireland UK
Female Deaths 103 7 5 4 119
Crude Rate 0.4 0.3 0.3 0.4 0.4
AS Rate 0.4 0.3 0.3 0.4 0.4
AS Rate - 95% LCL 0.3 0.1 0.0 0.0 0.3
AS Rate - 95% UCL 0.4 0.4 0.5 0.9 0.4
Male Deaths 129 15 7 2 153
Crude Rate 0.5 0.6 0.5 0.2 0.5
AS Rate 0.5 0.6 0.4 0.3 0.5
AS Rate - 95% LCL 0.4 0.3 0.1 0.0 0.4
AS Rate - 95% UCL 0.6 0.9 0.8 0.6 0.6
Persons Deaths 232 22 12 6 272
Crude Rate 0.4 0.4 0.4 0.3 0.4
AS Rate 0.4 0.4 0.4 0.4 0.4
AS Rate - 95% LCL 0.4 0.2 0.2 0.1 0.4
AS Rate - 95% UCL 0.5 0.6 0.6 0.6 0.5

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate Open a glossary item

References

  1. Data were provided by the Office for National Statistics on request, November 2019. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, June 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2018, C91.0.

Last reviewed:

Acute lymphoblastic leukaemia mortality is related to age, with the highest mortality rates being in older people. In the UK in 2016-2018, on average each year a fifth of deaths (20%) were in people aged 75 and over.[1-3] This is a much lower proportion of deaths in older age groups compared with most cancers.

Age-specific mortality rates remain steady from birth and rise steeply from around age 50-54. The highest rates are in the 90+ age group for females and the 80 to 84 age group for males. Mortality rates are similar between females and males in most age groups.

Acute Lymphoblastic Leukaemia (C91.0), Average Number of Deaths per Year and Age-Specific Mortality Rates per 100,000 Population, UK2016-2018

References

  1. Data were provided by the Office for National Statistics on request, November 2019. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, June 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2016-2018, ICD-10 C91.0.

Last reviewed:

Acute lymphoblastic leukaemia European age-standardised Open a glossary item (AS) mortality rates for females and males combined decreased by 50% in the UK between 1971-1973 and 2016-2018.[1-3] The decrease was larger in males than in females.

For females, acute lymphoblastic leukaemia AS mortality rates in the UK decreased by 46% between 1971-1973 and 2016-2018. For males, acute lymphoblastic leukaemia AS mortality rates in the UK decreased by 54% between 1971-1973 and 2016-2018.

Over the last decade in the UK (between 2006-2008 and 2016-2018), acute lymphoblastic leukaemia AS mortality rates for females and males combined remained stable. In females AS mortality rates remained stable, and in males rates remained stable.

Acute Lymphoblastic Leukaemia (C91.0), European Age-Standardised Mortality Rates per 100,000 Population, UK, 1971-2018

For most cancer types, mortality trends largely reflect incidence and survival trends. For example, rising mortality may reflect rising incidence and stable survival, while falling mortality may reflect rising incidence and rising survival.

Acute lymphoblastic leukaemia mortality rates have varied between age groups in females and males combined in the UK since the early 1970s.[1-3] Rates in 0-24s have decreased by 77%, in 25-49s have remained stable, in 50-59s have remained stable, in 60-69s have remained stable, in 70-79s have decreased by 39% and in 80+s have decreased by 47%.

Acute Lymphoblastic Leukaemia (C91.0), European Age-Standardised Mortality Rates per 100,000 Population, By Age, UK, 1971-2018

References

  1. Data were provided by the Office for National Statistics on request, November 2019. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, June 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1971-2018, C91.0.

Last reviewed:

There is no evidence for an association between acute lymphoblastic leukaemia (ALL) mortality and deprivation for either males or females in England.[1] England-wide data for 2007-2011 show European age-standardised Open a glossary item mortality rates are similar for both males and females living in the most deprived areas compared with the least deprived.[1]

Acute Lymphoblastic Leukaemia (C91.0), European Age-Standardised Mortality Rates by Deprivation Quintile, England, 2007-2011

The estimated deprivation gradient in ALL mortality between people living in the most and least deprived areas in England has not changed in the period 2002-2011.[1

References

  1. Cancer Research UK and National Cancer Intelligence Network. Cancer by deprivation in England: Incidence, 1996-2010, Mortality, 1997-2011. London: NCIN; 2014.

About this data

Data is for: England, 2007-2011, ICD-10 C91.0

Deprivation gradient statistics were calculated using mortality data for 2007-2011. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

Last reviewed:

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Acknowledgements

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