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Diagnosing liver cancer

Referral to a specialist for symptoms of liver cancer

Your GP should arrange for you to see a specialist or have tests if you have symptoms that could be due to cancer that started in the liver. This is called an urgent suspected cancer referral. 

Seeing your GP

It can be hard for GPs to decide who may have cancer and who might have a more minor condition. For some symptoms, your doctor may ask you to wait to see if the symptoms get better or respond to treatment, such as antibiotics.

You should contact your GP if your symptoms don't get better, or if they get worse.

UK referral guidelines

There are guidelines for GPs to help them decide who needs a referral. These vary slightly between the different UK nations. Your GP will use these guidelines as well as their own experience and judgement.

In England and Wales

Your doctor will consider an urgent referral for an ultrasound scan if you have a lump in the upper part of your tummy (abdomen) that feels like a swollen (enlarged) liver.

In Northern Ireland

In Northern Ireland the guidance groups together the symptoms of:

  • pancreatic cancer

  • cancer of the food pipe (oesophagus)

  • stomach cancer

  • cancer of the first part of your bowel (duodenum)

  • liver cancer

  • bile duct cancer

  • cancer of the gallbladder

Your GP should refer you urgently for an endoscopy or to see a specialist if you are any age, have indigestion and any of the following:

  • symptoms such as blood in your poo, or your poo is black or tar-looking due to bleeding in your ​

  • difficulty swallowing (dysphagia)

  • losing weight without trying to

  • being sick and this is not getting better

  • lack of ​ in the body (iron deficiency anaemia) – this is picked up with a blood test

  • a lump (mass) in the upper part of your tummy (abdomen)

  • an abnormal result from a test called a ​​ meal

Your GP should refer you urgently for an endoscopy if you are 55 years or older and you have recently developed indigestion that is unexplained.

Your GP should refer you urgently to see a specialist if you have:

  • difficulty swallowing 

  • unexplained pain in the upper part of your tummy and weight loss. You may or may not have back pain with this

  • a lump in the upper part of your tummy and you do not have indigestion

Some people with obstructive jaundice will have an urgent ultrasound. Your GP will tell you if this is necessary for you.

Your GP might refer you urgently to see a specialist if you have no sign of indigestion and you:

  • are being sick, this is not getting better and you are losing weight

  • have unexplained weight loss or have a lack of iron in your body

Your GP might refer you urgently to see a specialist if you have unexplained indigestion that is getting worse and you are known to have:

  • ​ 

  • abnormal cells (dysplasia)

  • inflammation and thinning of the stomach lining (atrophic gastritis)

  • changes to the lining of the food pipe and stomach that looks like the lining of the bowel (intestinal metaplasia)

  • had peptic ulcer surgery over 20 years ago

In Scotland

In Scotland the guidance groups the symptoms of cancer of the pancreas, liver, bile duct and gallbladder together. You should have an urgent referral if you have a condition called ​​ and this is not causing you any pain. 

Your GP should also refer you if you have unexplained weight loss, particularly if you are over 55, and you have one or more of the following: 

  • a lump (mass) in the upper area of your tummy

  • newly diagnosed diabetes

  • new and unexplained back pain

  • ongoing symptoms affecting the gastrointestinal tract (such as vomiting or feeling full after eating small amounts) and tests such as ​​ have not shown a cause

  • an abnormal area found on a scan

Read about tests to diagnose primary liver cancer

Other symptoms

Your GP will consider any other symptoms that you are having, so do mention these. They might also take into account whether you have any risk factors that affect your chances of developing a liver cancer.

Find out about risks and causes of liver cancer

If you're still worried

Sometimes you might feel that your GP is not concerned enough about your symptoms. If you think they should be more concerned, print this page and the symptoms page. Ask your GP to explain why they don’t think you need a referral.

Contact your GP again if your symptoms don't get better or you notice any new or unusual symptoms.

What should you do if you don’t get an appointment?

If your GP has referred you to a specialist, ask them when you should get your appointment. Contact them again if you don’t get one. Or some hospitals have a referral service you could try contacting if you know which hospital you are going to. Explain that you are waiting for an urgent suspected cancer referral.

Go to more information about an urgent referral, what to expect and questions to ask

Waiting times

Your hospital is working towards waiting time targets. For example, a target to find out whether you have cancer or not. And there are targets to start treatment if you are diagnosed with cancer. These are slightly different depending on where you live in the UK.

Find out about cancer waiting times

Last reviewed: 17 Mar 2025

Next review due: 17 Mar 2028

Seeing your GP when you have symptoms of liver cancer

See your GP if you notice a change that isn't normal for you or if you have any of the possible signs and symptoms of liver cancer.

Symptoms of liver cancer

Symptoms of liver cancer can include weight loss, jaundice, feeling sick, and a swollen or painful tummy (abdomen).

Tests for liver cancer

You have a number of tests to check for liver cancer. The tests you might have include blood tests and scans such as an ultrasound scan of the liver.

What is liver cancer?

Liver cancer is a cancer that starts in the liver. You might hear it called primary liver cancer.

Liver cancer main page

Primary liver cancer is cancer that started in the liver. This section is mainly about the most common type of liver cancer, hepatocellular carcinoma (HCC).

Secondary liver cancer

Secondary liver cancer is when a cancer that started somewhere else in the body has spread to the liver. It is also called liver metastases.

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