Liver cancer
Cancer that starts in the liver (primary liver cancer) doesn't usually cause symptoms in the early stages. If you do have symptoms, they can include:
weight loss
feeling or being sick
loss of appetite or feeling full after eating small amounts
yellowing of the skin and whites of the eyes (jaundice)
itching
swollen tummy (abdomen)
pain or discomfort in your abdomen
a lump in the right side of your abdomen
pain in your right shoulder or in your back
feeling weak or tired (fatigue)
high temperature (fever)
If you already have a liver condition such as cirrhosis, tell your doctor if you have any new or worsening symptoms.
Get tips on seeing your GP about your liver symptoms
This is weight loss when you are not trying to lose weight. This could be due to:
a loss of appetite
feeling full after eating small amounts
feeling or being sick
You may have pain in your tummy (upper abdomen).
A swollen (enlarged) liver can cause pain in your right shoulder or back. This is because the enlarged liver stimulates nerves that connect to nerves in the shoulder. This is called referred pain.
Jaundice is the yellowing of the skin and the whites of the eyes. It is caused by a blockage in the bile duct or your liver not working properly.
Liver cancer can cause swelling of the tummy (abdomen). This might be because:
the liver gets bigger from the growing cancer, and causes swelling on the right side of your abdomen
the cancer increases pressure in the liver causing blood to back up in the vessels (veins). This forces fluid out of the veins into the abdomen (ascites)
The increased pressure in the veins can make them swell so they might be seen under the surface of your abdomen. Ascites can also develop when the liver isn’t making enough blood protein (albumin).
A swollen abdomen might cause discomfort or pain, and a loss of appetite or feeling full quickly. It can also cause breathlessness or swollen feet.
Last reviewed: 13 Mar 2025
Next review due: 13 Mar 2028
Liver cancer is a cancer that starts in the liver. You might hear it called primary liver cancer.
You usually start by seeing your GP. They might refer you for tests or to a specialist if you have symptoms that could be caused by liver cancer.
Liver cancer is uncommon in the UK. Find out about factors that can increase your risk of developing it.
Liver cancer survival depends on many factors including the stage and type of your cancer.
Secondary liver cancer is when a cancer that started somewhere else in the body has spread to the liver. It is also called liver metastases.
Primary liver cancer is cancer that started in the liver. This section is mainly about the most common type of liver cancer, hepatocellular carcinoma (HCC).

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education
Search our clinical trials database for all cancer trials and studies recruiting in the UK.
Meet and chat to other cancer people affected by cancer.
Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.