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A trial of encorafenib, binimetinib and vemurafenib for melanoma (COLUMBUS)

Overview

Cancer types:

Melanoma, Secondary cancers, Skin cancer

Status:

Results

Phase:

Phase 3

Details

This trial compared 2 drugs called encorafenib and binimetinib with vemurafenib for melanoma skin cancer.

This trial was for people with melanoma skin cancer that had spread to nearby or to another part of the body (advanced melanoma). And whose melanoma cells had a change in the gene called BRAF.

Recruitment start: 12 September 2013

Recruitment end: 11 January 2016

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Mark Middleton

Supported by

Array Biopharma Inc

Experimental Cancer Medicine Centre (ECMC)

NIHR Clinical Research Network: Cancer

Novartis

Last reviewed: 16 January 2019

CRUK internal database number: 11136

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