Prostate cancer, Secondary cancers
Results
Phase 2
This trial looked at olaparib for men with prostate cancer that had spread elsewhere in the body. The men taking part had cancer that got worse despite hormone therapy and chemotherapy drugs called .
Cancer Research UK supported this trial.
The trial was open for people to join between 2012 and 2018. The team published results of the first part of the trial (TOPARP A) in 2015 and further results of the second part of the trial (TOPARP B) in 2020.
Recruitment start: 4 July 2012
Recruitment end: 19 June 2018
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Johann De Bono
AstraZeneca
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
Institute of Cancer Research (ICR)
NIHR Clinical Research Network: Cancer
The Royal Marsden NHS Foundation Trust
Prostate Cancer UK
The Prostate Cancer Foundation
This is Cancer Research UK trial number CRUK/11/029
Last reviewed: 18 January 2021
CRUK internal database number: 7399