Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study to understand more about soft tissue sarcoma
This study is looking at samples of confirmed and possible (suspected) soft tissue sarcomas to try to understand more about how they develop.
Soft tissue sarcomas are rare cancers that develop from the cells that make up soft tissue (for example, muscle and fat tissue). As soft tissue is present in all parts of the body, sarcomas can grow almost anywhere. Sarcomas often appear as a lump or swelling. But most lumps are not cancerous. Researchers want to look at the differences between cancerous and non cancerous (benign) lumps in various types of soft tissue, to understand more about how soft tissue sarcomas develop.
They will study tissue samples from people with sarcoma, or suspected sarcoma. They will look for and examine any abnormal molecules that may be in the tissue, including proteins and DNA. Where the team can collect suitable samples, they will use the tissue to develop cell lines. Cell lines are cells removed from the tissue that can continue to be grown in the laboratory. Cell lines will be useful for further studies, which may include testing and developing new drug treatments.
You will not have any direct benefit from taking part in this study, and it is unlikely to change your treatment plan in any way. But the result of the study will be used to help people with cancer in the future.
Who can enter
This study is only recruiting patients from Weston Park Hospital or The Royal Hallamshire Hospital in Sheffield. If you are suitable for the study, a member of your medical team will ask if you would like to take part. People taking part will
- Have, or their doctor thinks they may have, a soft tissue sarcoma
- Be at least 16 years old
You cannot enter this study if you would not be able to communicate easily with the study team for any reason.
This study will recruit 250 people.
Everyone taking part will give permission for the study team to
- Store and use any spare tissue removed from surgery or biopsies you have had, or may have
- Gather details about your medical history and current condition, from both you and your medical records
- Check your medical records from time to time to update their database on your condition
- Keep your tissue samples after this study to use for future research
You will not need to make any extra hospital visits to take part in this study.
You will not have any side effects as a result of taking part in this study.
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Experimental Cancer Medicine Centre (ECMC)
Sheffield Teaching Hospitals NHS Foundation Trust
Yorkshire Cancer Research