A study to find the best way of working out a woman's risk of breast cancer if she has a strong family history (FHRisk - additional participants)

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Breast cancer





This study is looking at improving the way specialists work out the risk of breast cancer in women who have a family history of the disease. It is part of a larger study called FHRisk. The researchers want more women to join the study as this will help them to improve the way they work out the risk.

Having a number of relatives who’ve had breast cancer (or some other cancers) can increase your risk of getting breast cancer. If you have a strong family history of breast cancer, a specialist can assess your individual risk. They base this on details of your family history and other factors such as whether or not you have children. And if so, the age you were when you had your first child.

But researchers know they can improve this assessment of risk by including other information.  In this study, they will take a small blood sample to carry out tests on your genes. The aim of the study is to work out the best way to predict a woman’s risk of breast cancer.

Who can enter

You may be able to join this study you attend the Family History Clinic in Manchester and are currently taking part in other research.

Trial design

If you agree to take part, the study team will ask you to give a blood sample. They will use this to look for certain gene changes that can affect breast cancer risk.

The researchers will ask you if you want to know the results of your blood test. If you do, a member of the research team will discuss them with you.

Hospital visits

There are no extra hospital visits. The research team can take the blood sample when you have an appointment at the Family History Clinic.

Side effects

You may have a small bruise after having a blood test.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Gareth Evans

Supported by

National Institute for Health Research (NIHR)
Nightingale Centre and Genesis Prevention Centre
The Genesis Breast Cancer Prevention Appeal
University Hospital of South Manchester NHS Foundation Trust

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:

Oracle 12029

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Deborah wanted to help other breast cancer patients in the future

A picture of Deborah

“Deborah agreed to take part in a trial as she was keen to help other cancer patients in the future. "If taking part in a trial means others might be helped then I’m very happy with that."

Last reviewed:

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