A study of prostate cancer in men aged 70 years and older (POCAMOS)

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Prostate cancer





This study is looking at the possibility of predicting future fitness levels in men over 70 after they have treatment for prostate cancer. The trial is for men with prostate cancer who are having radiotherapy.

More about this trial

Doctors use radiotherapy to treat prostate cancer. As with all treatments, radiotherapy has side effects that can affect your fitness afterwards. In this study, the researchers want to ask men some questions about their daily activities, general fitness and appetite over a number of years. They want to find out if these simple questionnaires can help them predict how treatment may affect men in the future.

Please note that you won’t get any direct benefit from taking part in this study and it won’t affect your treatment. But the information collected may help older men with prostate cancer in the future.

Who can enter

You may be able to join this study if you go to Brighton and Sussex University Hospitals NHS Trust, Eastbourne District General Hospital or Worthing Hospital and all of the following apply

You cannot join this study if any of these apply

Trial design

The study team need 250 men to join.

The study team will ask you some questions about your daily activities, your general health and fitness, and your appetite. They will do this before you start your radiotherapy. It will take about 10 to 15 minutes.

They would also like to contact you 3 and 6 months, 1, 2, 5 and 10 years later to ask a few questions. They can do this over the telephone. It will take about 5 minutes.

They will ask your permission to look at your medical records to take details of your diagnosis, treatment and any side effects from treatment you have. They will also contact your GP for your medical history.

The researchers will ask for a blood sample. They will also ask your permission to get a sample of your cancer tissue that was removed when you had a biopsy Open a glossary item. They will use these samples to look for substances called biomarkers Open a glossary item. This is to try and develop new ways of predicting how treatment may affect fitness in the future. If you don’t want to give these samples for research, you don’t have to. You can still take part in the study.

Hospital visits

The researchers will ask you the questions at your routine appointments or over the telephone.

Side effects

If you agree to give the blood sample, you may have some minor bruising or bleeding where it is taken.

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Alastair Ring

Supported by

Brighton and Sussex University Hospitals NHS Trust
Experimental Cancer Medicine Centre (ECMC)
Sussex Cancer Fund

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Keith took part in a trial looking into hormone therapy

A picture of Keith

"Health wise I am feeling great. I am a big supporter of trials - it allows new treatments and drugs to be brought in.”

Last reviewed:

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