Acute myeloid leukaemia (AML) mortality statistics

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Deaths

Deaths from acute myeloid leukaemia, 2016-2018, UK.

Proportion of all deaths

Percentage acute myeloid leukaemia contributes to total cancer deaths, 2016-2018, UK

Age

Peak rate of acute myeloid leukaemia deaths, 2016-2018, UK

 

Trend over time

Change in acute myeloid leukaemia mortality rates since the early 1970s, UK

Acute myeloid leukaemia accounted for 2% of all cancer deaths in the UK in 2018.[1-3]

In females in the UK, acute myeloid leukaemia accounted for 1% of all female cancer deaths. In males in the UK, it accounted for 2% of all male cancer deaths).

42% of acute myeloid leukaemia deaths in the UK are in females, and 58% are in males (2018).

Acute myeloid leukaemia mortality rates (European age-standardised (AS) rates Open a glossary item) for persons are significantly lower than the UK average in Northern Ireland and similar to the UK average in all other UK constituent countries.

For acute myeloid leukaemia there are mortality differences between countries despite there being no such differences in incidence.

Acute Myeloid Leukaemia (C92.0, C92.4, C92.5, C92.6, C92.8, C93.0, C94.0, C94.2), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2018

  England Scotland Wales Northern Ireland UK
Female Deaths 912 99 64 15 1,090
Crude Rate 3.2 3.5 4.0 1.6 3.2
AS Rate 3.1 3.3 3.5 1.6 3.1
AS Rate - 95% LCL 2.9 2.7 2.7 0.8 3.0
AS Rate - 95% UCL 3.3 4.0 4.4 2.5 3.3
Male Deaths 1,269 122 77 21 1,489
Crude Rate 4.6 4.6 5.0 2.3 4.5
AS Rate 5.3 5.2 5.3 2.9 5.3
AS Rate - 95% LCL 5.0 4.3 4.1 1.7 5.0
AS Rate - 95% UCL 5.6 6.2 6.4 4.2 5.5
Persons Deaths 2,181 221 141 36 2,579
Crude Rate 3.9 4.1 4.5 1.9 3.9
AS Rate 4.1 4.2 4.2 2.2 4.1
AS Rate - 95% LCL 3.9 3.6 3.5 1.5 3.9
AS Rate - 95% UCL 4.3 4.7 4.9 3.0 4.2

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate Open a glossary item

References

  1. Data were provided by the Office for National Statistics on request, November 2019. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, June 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2018, C92.0, C92.4, C92.5, C92.6, C92.8, C93.0, C94.0, C94.2.

Last reviewed:

Acute myeloid leukaemia mortality is strongly related to age, with the highest mortality rates being in older people. In the UK in 2016-2018, on average each year more than half of deaths (53%) were in people aged 75 and over.[1-3] This largely reflects higher incidence and lower survival for acute myeloid leukaemia in older people.

Age-specific mortality rates rise steadily from around age 50-54 and more steeply from around age 65-69. The highest rates are in the 85 to 89 age group for females and males. Mortality rates are significantly lower in females than males in a number of (mainly older) age groups.The gap is widest at age 75 to 79, when the age-specific mortality rate is 1.9 times lower in females than males.

Acute Myeloid Leukaemia (C92.0, C92.4, C92.5, C92.6, C92.8, C93.0, C94.0, C94.2), Average Number of Deaths per Year and Age-Specific Mortality Rates per 100,000 Population, UK, 2016-2018

References

  1. Data were provided by the Office for National Statistics on request, November 2019. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, June 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2016-2018, ICD-10 C92.0, C92.4, C92.5, C92.6, C92.8, C93.0, C94.0, C94.2.

Last reviewed:

Acute myeloid leukaemia European age-standardised Open a glossary item (AS) mortality rates for females and males combined increased by 55% in the UK between 1971-1973 and 2016-2018.[1-3] The increase was larger in males than in females.

For females, acute myeloid leukaemia AS mortality rates in the UK increased by 38% between 1971-1973 and 2016-2018. For males, acute myeloid leukaemia AS mortality rates in the UK increased by 63% between 1971-1973 and 2016-2018.

Over the last decade in the UK (between 2006-2008 and 2016-2018), acute myeloid leukaemia AS mortality rates for females and males combined remained stable. In females AS mortality rates remained stable, and in males rates remained stable.

Acute Myeloid Leukaemia (C92.0, C92.4, C92.5, C92.6, C92.8, C93.0, C94.0, C94.2), European Age-Standardised Mortality Rates per 100,000 Population, UK, 1971-2018

For most cancer types, mortality trends largely reflect incidence and survival trends. For example, rising mortality may reflect rising incidence and stable survival, while falling mortality may reflect rising incidence and rising survival.

Acute myeloid leukaemia mortality rates have varied between age groups in females and males combined in the UK since the early 1970s.[1-3] Rates in 0-24s have decreased by 68%, in 25-49s have decreased by 61%, in 50-59s have decreased by 25%, in 60-69s have increased by 35%, in 70-79s have increased by 121% and in 80+s have increased by 189%.

Acute Myeloid Leukaemia (C92.0, C92.4, C92.5, C92.6, C92.8, C93.0, C94.0, C94.2), European Age-Standardised Mortality Rates per 100,000 Population, By Age, UK, 1971-2018

References

  1. Data were provided by the Office for National Statistics on request, November 2019. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2019. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, June 2020. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1971-2018, C92.0, C92.4, C92.5, C92.6, C92.8, C93.0, C94.0, C94.2.

Last reviewed:

There is no evidence for an association between acute myeloid leukaemia (AML) mortality and deprivation for either males or females in England.[1] England-wide data for 2007-2011 show European age-standardised Open a glossary item mortality rates are similar for both males and females living in the most deprived areas compared with the least deprived.[1]

Acute Myeloid Leukaemia (C92.0,C92.4,C92.5,C93.0,C94.0,C94.2), European Age-Standardised Mortality Rates by Deprivation Quintile, England, 2007-2011

The estimated deprivation gradient in AML mortality between people living in the most and least deprived areas in England has not changed in the period 2002-2011.[1]

References

  1. Cancer Research UK and National Cancer Intelligence Network. Cancer by deprivation in England: Incidence, 1996-2010, Mortality, 1997-2011. London: NCIN; 2014.

About this data

Data is for: England, 2007-2011, ICD-10 C92.0,C92.4,C92.5,C93.0,C94.0,C94.2

Deprivation gradient statistics were calculated using mortality data for 2007-2011. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

Last reviewed:

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Acknowledgements

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