A trial looking at cisplatin, gemcitabine and sunitinib for advanced transitional cell cancer of the urinary system (SUCCINCT)

This trial looked at a drug called sunitinib alongside chemotherapy for transitional cell cancer. It was for people whose cancer had grown into surrounding tissue (is locally advanced) or had spread to another part of their body. The trial was supported by Cancer Research UK.

Transitional cells (also called urothelial cells) are a part of the urinary system. The urinary system filters waste products from the blood and makes urine. Transitional cells line the centre of each kidney (renal pelvis), the bladder and the tubes that drain urine from the kidneys to the bladder (ureters). So you can get transitional cell cancer in the kidney, bladder or ureters.