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A trial using circulating tumour DNA to work out when to switch between targeted treatment and immunotherapy for melanoma (CAcTUS)

Overview

Cancer types:

Melanoma, Secondary cancers

Status:

Closed

Phase:

Pilot

Details

This trial is looking at whether measuring can help doctors work out the best time to switch treatment for people with melanoma.

It is for people who:

  • can’t have surgery to remove the melanoma or it has spread elsewhere in the body and

  • have melanoma cells with a specific gene change in the BRAF gene called BRAF VE 600

Recruitment start: 2 May 2019

Recruitment end: 30 September 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Paul Lorigan

Supported by

Bristol-Myers Squibb

The Christie NHS Foundation Trust

University of Manchester

Last reviewed: 12 October 2023

CRUK internal database number: 17883

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