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A trial using buparlisib with trastuzumab for breast cancer that has spread

Overview

Cancer types:

Breast cancer, Cancer spread to the brain, Secondary cancers

Status:

Results

Phase:

Phase 1/2

Details

This trial looked at buparlisib (BKM120) with trastuzumab for breast cancer.

It was for people who had :

  • that had spread to another part of the body (advanced) or into the nearby tissue (locally advanced)

  • and had got worse while having trastuzumab

The trial was open for people to join between 2011 and 2014. The team published the results in 2018.

Recruitment start: 1 July 2011

Recruitment end: 10 January 2014

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Karla Martins

Supported by

Experimental Cancer Medicine Centre (ECMC)

National Institute for Health Research Cancer Research Network (NCRN)

Novartis

Last reviewed: 25 Aug 2024

CRUK internal database number: 8614

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