A trial looking at sonesitatug vedotin, rilvegostomig and chemotherapy for cancer of the stomach (GEMINI GASTRIC Sub study 4)

Overview

Cancer types:

Oesophageal cancer, Secondary cancers, Stomach cancer

Status:

Open

Phase:

Phase 2

Details

This trial is looking at sonesitatug vedotin and rilvegostomig with capecitabine or 5-FU for stomach cancer and cancer where the food pipe joins the stomach.

It is open to people with stomach cancer and cancer where the food pipe joins the stomach (gastro oesophageal cancer) that:

  • has spread to another part of the body or cannot be removed with surgery and

  • has not been treated

You pronounce sonesitatug vedotin as soh-nee-sit-uh-tug veh-doh-tin. Sonesitatug vedotin is also called AZD0901.

You pronounce rilvegostomig as ril–veh–gost-oh-mig.

Recruitment start: 13 May 2026

Recruitment end: 30 June 2027

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Elizabeth Smyth

Supported by

AstraZeneca

Last reviewed: 21 Sept 2026

CRUK internal database number: 20193

The Dangoor Education logo.

Dangoor Education

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education

Patient Information Forum. Trusted Information Creator.
Plain English Campaign award.

Help and support

An icon of a hand shake.

Find a Clinical Trial

Search our clinical trials database for all cancer trials and studies recruiting in the UK.

An icon of two speech bubbles, indicating a conversation.

Cancer Chat forum

Connect with other people affected by cancer and share your experiences.

An icon of a landline phone.

Nurse helpline

Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.