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A trial of trastuzumab deruxtecan for stomach cancer (DESTINY-Gastric03)

Overview

Cancer types:

Secondary cancers, Stomach cancer

Status:

Closed

Phase:

Phase 1/2

Details

This trial is looking at trastuzumab deruxtecan for stomach cancer that has spread into the nearby tissue or to another part of the body.

It is also looking at adding another drug called pembrolizumab to trastuzumab deruxtecan. This is to find out whether this combination might work better than trastuzumab deruxtecan on its own.

The trial is open to people with stomach cancer and cancer where the food pipe meets the stomach (gastro oesophageal junction cancer) that:

  • has many receptors (HER2 positive)

  • and doctors can’t remove by surgery

Recruitment start: 15 July 2021

Recruitment end: 1 August 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Starling

Supported by

AstraZeneca

Daiichi Sankyo

Last reviewed: 1 September 2022

CRUK internal database number: 17685

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