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A trial of targeted drugs and chemotherapy for children and young people with cancer (eSMART)

Overview

Cancer types:

All cancer types, Children's cancers

Status:

Open

Phase:

Phase 1/2

Details

This trial is for children, teenagers and young adults whose cancer has come back or treatment has stopped working.

Those taking part need to have had a tissue sample taken of their cancer () for the SMPaeds programme. This research looks for certain changes () in the of the cancer cells.

This trial is for children, teenagers and young people up to their 18th birthday. We use the term ‘you’, but of course if you are a parent, we are referring to your child.

Cancer Research UK supports this trial.

Recruitment start: 20 December 2019

Recruitment end: 28 February 2026

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Lynley Marshall

Supported by

Cancer Research UK

Institute Gustave-Roussy

University of Birmingham

Innovative Therapies for Children with Cancer European Consortium (ITCC)

Other information

This is Cancer Research UK trial number CRUK/17/013.

Last reviewed: 4 June 2025

CRUK internal database number: 14951

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