A trial of PLX2853 with ruxolitinib for myelofibrosis (PROMise)

Please note

This trial is no longer recruiting patients. We hope to add results when they are available.

Overview

Cancer types:

Myelofibrosis

Status:

Closed

Phase:

Phase 1

Details

This trial is adding PLX2853 to ruxolitinib. It is for people with myelofibrosis who are already taking ruxolitinib but it isn’t working too well for them.

Cancer Research UK supports this trial.

Recruitment start: 28 April 2021

Recruitment end: 30 June 2025

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Adam Mead

Supported by

Cancer Research UK

University of Birmingham

Other information

This is Cancer Research UK trial number CRUK/18/008.

Last reviewed: 29 Jun 2025

CRUK internal database number: 16447

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