A trial of pembrolizumab and chemotherapy for triple negative breast cancer (Keynote-355)

Overview

Cancer types:

Breast cancer, Secondary cancers

Status:

Results

Phase:

Phase 3

Details

This trial was for people with triple negative breast cancer that had come back or spread to another part of the body.

Triple negative breast cancer means cancer that doesn’t have receptors for:

  • the hormone oestrogen

  • the hormone progesterone

  • the protein HER2

People could join the trial between 2017 and 2018. The team published results between 2020 and 2024.

There is a link to more information in the ‘Summary of results’ section below.

Recruitment start: 9 January 2017

Recruitment end: 12 June 2018

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Peter Schmid

Supported by

Merck Sharp & Dohme Ltd

Last reviewed: 17 Jul 2026

CRUK internal database number: 14853

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