A trial of pembrolizumab and chemotherapy for breast cancer (KEYNOTE-B49)

Please note

This trial is no longer recruiting patients. We hope to add results when they are available.

Overview

Breast cancer, Secondary cancers

Closed

Phase 3

This trial is looking at adding pembrolizumab to chemotherapy for breast cancer that has come back or spread.

It is for people whose cancer has:

come back in the same area of the breast and you can’t have an operation to remove it or it has spread elsewhere in the body
a large number of receptors for the hormone oestrogen ()
none or a small number of the HER2 receptors ()
cells that have certain proteins (receptors) called PD-L1 on the surface (PD-L1 positive)