Prostate cancer
Open
Phase 2/3
This trial is looking at radiotherapy to nearby lymph nodes in addition to radiotherapy to the prostate. It is open to men having radiotherapy for the first time. You have it alongside .
The that doctors treat with radiotherapy include:
those in the area between the hip bones (pelvic lymph nodes)
those that lie in front of the spine in the lower back near a main blood vessel in the body (para-aortic lymph nodes)
Cancer Research UK supports this trial.
Recruitment start: 25 June 2021
Recruitment end: 30 September 2027
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Julia Murray
Cancer Research UK
Institute of Cancer Research (ICR)
This is Cancer Research UK trial number CRUK/19/016.
The trial team have made a short video about the trial. Go to the PEARLS trial website(link is external) to watch it.
Last reviewed: 16 April 2025
CRUK internal database number: 17185