Blood cancers, Cell type, Chronic leukaemia, Chronic lymphocytic leukaemia (CLL), Leukaemia, Lymphoma
Open
Phase 2
This trial is looking at zilovertamab vedotin by itself or in combination with nemtabrutinib for people with B cell lymphomas and B cell leukaemia.
B cell lymphoma and B cell leukaemia are also called B cells cancers.
It is open to people with one of the following B cell cancers that has come back or got worse during treatment:
Richter transformation . This is also called Richter’s syndrome.
You pronounce zilovertamab vedotin as zi-lov-er-ta-mab ve-dot-in.
You pronounce nemtabrutinib as nem-tab-rut-i-nib.
Recruitment start: 31 July 2023
Recruitment end: 22 April 2027
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Satyen Gohil
Merck Sharp & Dohme
Last reviewed: 15 May 2025
CRUK internal database number: 19601