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A trial looking at izalontamab brengitecan for breast cancer that has come back or spread (IZABRIGHT-Breast01)

Overview

Cancer types:

Breast cancer, Secondary cancers

Status:

Open

Phase:

Phase 2/3

Details

This trial is looking at a drug called izalontamab brengitecan for . It is comparing this to .

It is for people who:

  • have or

  • have breast cancer that has low levels of receptors for the hormones and and no receptors for . Your doctor will know this.

You pronounce izalontamab brengitecan as iz-uh-lon-too-mab braan-jit-eh-can.

Recruitment start: 1 October 2025

Recruitment end: 30 June 2028

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Peter Schmid

Supported by

Bristol-Myers Squibb

Last reviewed: 21 May 2026

CRUK internal database number: 20115

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