Oesophageal cancer
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This trial is offering people who have heartburn, indigestion or acid reflux a Heartburn Health Check. This is the capsule sponge test.
This could help find health problems in the food pipe (oesophagus), including cancer.
There are 2 parts to BEST4:
Heartburn Health Programme and BEST4 Screening
This summary is about the Heartburn Health Programme and BEST4 Screening part of the trial.
Recruitment start: 18 November 2024
Recruitment end: 26 December 2026
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Rebecca Fitzgerald
Cancer Research UK
The University of Cambridge
Cambridge University Hospitals NHS Foundation Trust
NIHR Health Technology Assessment (HTA) programme
There is more information about this trial on the BEST4 trial website.
You can also find out more about the Heartburn Health Programme.
This is Cancer Research UK trial number CRUK/22/005.
Last reviewed: 04 Sept 2025
CRUK internal database number: 19481
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