Lung cancer, Non small cell lung cancer (NSCLC)
Open
Phase 3
This trial is looking at adding calderasib to durvalumab for non small cell lung cancer.
It is open to people who:
have non small cell lung cancer that has grown or spread in the chest but has not spread to other parts of the body
can’t or don’t want to have surgery to treat their cancer
have a gene change () called KRAS G12C in their lung cancer cells
You pronounce calderasib as kal-dair-ah-sib.
Recruitment start: 10 September 2026
Recruitment end: 31 May 2031
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Pooja Bhatnagar
Merck Sharp & Dohme Ltd
Last reviewed: 14 Oct 2026
CRUK internal database number: 20195