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A trial looking at durvalumab for rectal cancer (PRIME RT)

Overview

Cancer types:

Bowel (colorectal) cancer, Rectal cancer

Status:

Results

Phase:

Phase 2

Details

This trial looked at durvalumab and radiotherapy for cancer of the back passage (rectal cancer). It was for people whose cancer had grown into the bowel wall, but had not spread to another part of the body.

The trial was supported by Cancer Research UK. People could join the trial between 2021 and 2023. The team presented the results at a conference in 2025.

Recruitment start: 15 January 2021

Recruitment end: 24 May 2023

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Mr Campbell Roxburgh

Supported by

AstraZeneca

Cancer Research UK

University of Glasgow

NHS Greater Glasgow and Clyde

Last reviewed: 14 May 2026

CRUK internal database number: 17187

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