All cancer types
Open
Phase 1
This trial is looking at adding a new drug called BAY 3498264 to sotorasib for .
It is for people whose cancer:
has a KRAS G12C gene change () and
has grown into surrounding tissues or spread to another part of the body
A solid cancer is any cancer apart from a blood cancer such as leukaemia, lymphoma and myeloma.
Recruitment start: 1 February 2025
Recruitment end: 30 November 2027
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Matthew Krebs
Bayer
Last reviewed: 19 Nov 2025
CRUK internal database number: 20065