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A trial looking at adaptive therapy with carboplatin chemotherapy for advanced ovarian cancer (ACTOv)

Overview

Cancer types:

Ovarian cancer, Secondary cancers

Status:

Open

Phase:

Phase 2

Details

This trial is looking at a new way of giving carboplatin chemotherapy called adaptive therapy. It is comparing this to having standard carboplatin chemotherapy for ovarian cancer.

It is for women whose cancer has come back after . And who have one of the following types of cancer:

  • epithelial ovarian cancer

  • fallopian tube cancer

  • primary peritoneal cancer

These cancers are treated in the same way, so when we use the term ovarian cancer in this summary, we are referring to all three.

Recruitment start: 10 March 2023

Recruitment end: 30 November 2026

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Michelle Lockley

Supported by

Barts Charity

Anticancer Fund

University College London (UCL)

Last reviewed: 16 Sept 2025

CRUK internal database number: 19996

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