A study of lung cancer in people who have never smoked (OLIVE)
Cancer type:
Status:
Phase:
This study is looking at understanding more about lung cancer in people who have never smoked.
A never smoker is someone who during their lifetime has smoked less than:
- 100 cigarettes or
- 75 grams of heated tobacco
More about this trial
There are several known risk factors for developing lung cancer. The most significant one is smoking. However a number of people who have never smoked also develop lung cancer.
In this study, researchers want to look at the medical notes of people who have never smoked and develop lung cancer. They want to find information about their risks, symptoms and outcomes.
The aim of the study is to identify the risks, symptoms and outcomes of lung cancer for people who have never smoked.
Please note taking part will not change your care or treatment. You might not get any benefit from taking part but the information may help people in the future.
Who can enter
The following bullet points are a summary of the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if both of these apply. You:
- have been diagnosed or treated for lung cancer that started in the lung
- are at least 18 years old
Who can’t take part
You cannot join this study if any of these apply. You:
- have smoked more than 100 cigarettes during your lifetime
- have smoked more than 75 grams of heated tobacco during your lifetime
- have or had a prescription for
nicotine 
replacement therapy
Trial design
This is an observation study. The team need 225 people to take part.
Taking part will not change your care or treatment.
The study team will ask your permission to see your medical notes at the hospital and at your GP. The information they will look at includes:
- personal information such as your age and cultural background (ethnicity)
- any other medical problems you might have
- information about your cancer and treatment
The team will look at your medical notes for 5 years.
In future they may want to collect some other information. This could be about the amount of pollution where you live and work. They will always ask your permission to do so before they collect it.
All information the team collect is kept in a safe and secure place. The team remove personal information, such as your name and date of birth.
Hospital visits
There are no extra hospital visits if you take part in the study.
Side effects
The study team do not expect there to be any side effects.
Location
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Professor Neal Navani
Supported by
National Institute for Health Research (NIHR) Biomedical Research Centre
Ruth Strauss Foundation
University College London (UCL)
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
Last review date
CRUK internal database number:
Last reviewed:
Dangoor Education since 2010.
