A study looking at surovatamig for B cell acute lymphoblastic leukaemia (SYRUS)

Overview

Cancer types:

Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Blood cancers, Children's cancers, Leukaemia

Status:

Open

Phase:

Phase 1/2

Details

This study is looking at surovatamig for B cell acute lymphoblastic leukaemia in young people and adults.

It is open to young people and adults with B cell acute lymphoblastic leukaemia (B cell ALL):

  • that has come back after treatment ()

  • where treatment has stopped working ()

You pronounce surovatamig as sur-roh-vah-tah-mig. Surovatamig is also called AZD0486.

Please note, we use the term ‘you’ in this summary. If you are a parent of a child with B cell acute lymphocytic leukaemia, we are referring to your child.

Recruitment start: 16 September 2026

Recruitment end: 12 July 2027

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Bela Wrench

Supported by

AstraZeneca

Last reviewed: 22 Oct 2026

CRUK internal database number: 20190

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