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A study looking at BE-CAR7 therapy for children and young people with acute lymphocytic leukaemia (TvT CAR7)

Overview

Cancer types:

Acute lymphoblastic leukaemia (ALL), Blood cancers, Children's cancers

Status:

Open

Phase:

Phase 1

Details

This study is looking at BE-CAR7 therapy for a type of acute lymphocytic leukaemia (ALL) called T cell ALL. It is for children and young people whose leukaemia is () to treatment or has come back after treatment.

This study is only for children and young people who are due to have a donor stem cell transplant at Great Ormond Street Hospital for Children NHS Foundation Trust.

Please note, we use the term ‘you’ in this summary, but of course if you are a parent of a child with cancer, we are referring to your child.

Recruitment start: 14 April 2022

Recruitment end: 30 June 2027

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Waseem Qasim

Supported by

Great Ormond Street Hospital for Children NHS Foundation Trust

Great Ormond Street Hospital Children’s Charity

Medical Research Council (MRC)

Wellcome Trust

Last reviewed: 20 Apr 2026

CRUK internal database number: 20002

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