A study looking at developing new test to diagnose prostate cancer

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Prostate cancer





This study is looking at using urine and semen samples to develop new tests to diagnose prostate cancer.

It is open to men who have prostate cancer and who are going to Sunderland Royal Hospital.

More about this trial

If you have symptoms of prostate cancer you see your GP and have a digital rectal examination (DRE) and a prostate-specific antigen (PSA) blood test.

Your GP will refer you to a specialist if needed. Your specialist might take a sample of prostate tissue (biopsy Open a glossary item) to confirm a diagnosis of prostate cancer.

Researchers are looking for new ways to diagnose prostate cancer using urine or semen samples. They need to collect a large number of urine and semen samples so they can develop these new tests.

You won’t have any direct benefit from taking part in this study but the researchers hope that in the future these tests could be used to see who is most likely to have prostate cancer. This will mean that only the people who really need a biopsy have this test.  

Who can enter

The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.

You may be able to join this study if you:

  • Have prostate cancer
  • Are going to the Sunderland Royal Hospital
  • Are at least 18 years old

You cannot join this study if any of these apply.

  • You are having hormone therapy
  • You have had a biopsy within 6 weeks of joining the study
  • You have inflammation of the prostate (prostatitis)
  • You have kidney stones (calculi) or bladder stones
  • You have had bladder cancer, kidney (renal) cancer or another cancer that has spread to part of your urinary tract (kidneys, ureters Open a glossary item, bladder, or urethra Open a glossary item)
  • Your doctor needs to use all of your semen sample

Trial design

As part of your routine clinic appointment you will be asked to give a urine sample. The study team will ask to use any excess urine from this sample for their research.

You might be asked to bring a semen sample at your next routine appointment.

The team might ask you to bring more samples of urine or semen at future clinic appointments.

Taking part in this study will not affect any tests or treatment you might need. 

Hospital visits

There are no extra hospital visits in this study.

Side effects

There are no side effects. 

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Mr Stuart McCracken

Supported by

Arquer Diagnostics Ltd

Questions about cancer? Contact our information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Keith took part in a trial looking into hormone therapy

A picture of Keith

"Health wise I am feeling great. I am a big supporter of trials - it allows new treatments and drugs to be brought in.”

Last reviewed:

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