Cancer Research UK logo.
SearchDonate
  • Search

A study looking at AUTO1 for children and teenagers with B cell leukaemia or B cell lymphoma

Overview

Cancer types:

Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Blood cancers, Children's cancers, High grade lymphoma, Leukaemia, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Open

Phase:

Phase 1

Details

This study is looking at a type of CAR T-cell therapy called AUTO1 (also called obe-cel) for children and teenagers with B cell or B cell .

It is open to children and teenagers with a B cell cancer that has come back or the treatment has stopped working.

We use the term ‘you’ in this summary, but if you are a parent we are referring to your child.

Please note

At the moment the team are not recruiting children and teenagers with B cell acute lymphocytic leukaemia.

Recruitment start: 31 October 2023

Recruitment end: 31 March 2027

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Sarah Ghorashian

Supported by

Autolus Limited

Last reviewed: 08 Jan 2026

CRUK internal database number: 20022

The Dangoor Education logo.

Dangoor Education

About Cancer generously supported by Dangoor Education since 2010. Learn more about Dangoor Education

Patient Information Forum. Trusted Information Creator.
Plain English Campaign award.

Help and support

An icon of a hand shake.

Find a Clinical Trial

Search our clinical trials database for all cancer trials and studies recruiting in the UK.

An icon of two speech bubbles, indicating a conversation.

Cancer Chat forum

Connect with other people affected by cancer and share your experiences.

An icon of a landline phone.

Nurse helpline

Questions about cancer? Call freephone 0808 800 40 40 from 9 to 5 - Monday to Friday. Alternatively, you can email us.