Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Blood cancers, Children's cancers, High grade lymphoma, Leukaemia, Lymphoma, Non-Hodgkin lymphoma (NHL)
Open
Phase 1
This study is looking at a type of CAR T-cell therapy called AUTO1 (also called obe-cel) for children and teenagers with B cell or B cell .
It is open to children and teenagers with a B cell cancer that has come back or the treatment has stopped working.
We use the term ‘you’ in this summary, but if you are a parent we are referring to your child.
At the moment the team are not recruiting children and teenagers with B cell acute lymphocytic leukaemia.
Recruitment start: 31 October 2023
Recruitment end: 31 March 2027
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Sarah Ghorashian
Autolus Limited
Last reviewed: 08 Jan 2026
CRUK internal database number: 20022