Stages, types and grades of pancreatic cancer

Stage 4 pancreatic cancer

Stage 4 is part of the number staging system. It may also be called advanced or metastatic pancreatic cancer. Treatment aims to help you live longer and control or prevent symptoms.

Pancreatic cancer can start in different types of .

Doctors call pancreatic cancer that starts in the cells that make digestive juices exocrine pancreatic cancer. The information on this page is about a type of exocrine pancreatic cancer called pancreatic . It is the most common type of exocrine pancreatic cancer.

Find out more about the types of pancreatic cancer

Pancreatic cancer can also start in cells that make hormones. This is called endocrine pancreatic cancer or pancreatic neuroendocrine cancer.

Doctors stage and treat these 2 types of pancreatic cancer differently.

Read about staging for pancreatic neuroendocrine cancer

Staging pancreatic cancer

The stage of a cancer tells your doctor about its size and whether it has spread. Your doctor gets information from your tests and scans to find the stage.

There are 4 number stages of pancreatic cancer, called stage 1 to 4.

Doctors can also use the TNM system to stage pancreatic cancer. TNM stands for Tumour, Node, Metastases.

Find out more about the TNM staging system for pancreatic cancer

What is stage 4 pancreatic cancer?

Stage 4 means that the cancer has spread to other areas of the body, such as the liver or lungs. The original (primary) cancer can be any size. And there may or may not be cancer cells in the nearby .

Diagram showing M1 pancreatic cancer from the TNM staging system.

In TNM staging, this is the same as Any T, Any N, M1.

Treatment for stage 4 pancreatic cancer

Knowing the cancer stage helps your doctor to decide which treatment to recommend. Treatment also depends on:

  • your general health and level of fitness

  • where the cancer has spread to

The stage of the cancer and these other factors can also give your doctor an idea about your outlook (prognosis).

Unfortunately, treatment won’t cure stage 4 pancreatic cancer. But it might help you live longer and relieve symptoms. Doctors call this .

The main treatment for stage 4 pancreatic cancer is . Which chemotherapy you have depends on how well you are. And you might have your treatment as part of a clinical trial.

Other treatments

Other palliative treatments for stage 4 pancreatic cancer include:

  • radiotherapy - this may help control symptoms such as pain from cancer that has spread to nearby lymph nodes or your bones

  • a procedure to prevent or relieve symptoms. For example, you may have a small tube (stent) put into the bile duct. This helps clear a blockage and prevents symptoms such as jaundice

  • medicines to help with pain control or other symptoms such as sickness

Read more about controlling symptoms of advanced pancreatic cancer

Palliative care

aims to relieve symptoms of cancer and improve your quality of life. You can have it at any stage after a diagnosis of advanced cancer.

People who are too unwell to have chemotherapy or other procedures to help relieve side effects can benefit from palliative care. This can be either in the hospital or at home.

Find out more about palliative care

Other stages of pancreatic cancer

Last reviewed: 20 Aug 2026

Next review due: 20 Aug 2029

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