Stages, types and grades of pancreatic cancer

TNM staging for pancreatic cancer

TNM stands for Tumour, Node, and Metastasis. It is one of the staging systems for pancreatic cancer. The stage tells your doctor about the size of the cancer and if it has spread.

Pancreatic cancer can start in different types of .

Doctors call pancreatic cancer that starts in the cells that make digestive juices exocrine pancreatic cancer. The information on this page is about a type of exocrine pancreatic cancer called pancreatic . It is the most common type of exocrine pancreatic cancer.

Find out more about the types of pancreatic cancer

Pancreatic cancer can also start in cells that make hormones. This is called endocrine pancreatic cancer or pancreatic neuroendocrine cancer.

Doctors stage and treat these 2 types of pancreatic cancer differently.

Read about staging for pancreatic neuroendocrine cancer

How does my doctor decide the stage?

The tests and scans you have give your doctor some information about the stage. But they may not be able to tell you exactly until after surgery, if you are able to have it.

Knowing the stage of the cancer helps your doctor recommend the best treatment for you.

There are different ways to describe the stage of pancreatic cancer. Doctors may also use the number staging system.

Find out about the number staging system

Tumour (T)

Tumour (T) describes the size and depth of the tumour (area of cancer).

Tis (carcinoma in situ)

This can be either:

  • a very early stage pancreatic cancer that hasn't grown into the deeper layers of the pancreas - it is uncommon for pancreatic cancer to be diagnosed this early

  • abnormal cells in the pancreas. This isn’t cancer but can develop into cancer in the future

T1

This means the cancer is inside the pancreas and is 2cm or less in any direction.

Diagram showing T1 cancer of the pancreas.

T1 is split into 3 stages:

  • T1a means the cancer is no more than 0.5cm 

  • T1b means the cancer is more than 0.5cm but less than 1cm

  • T1c means the cancer is between 1cm and 2cm

T2

This means the cancer is more than 2cm but no bigger than 4cm in any direction.

Diagram showing T2 cancer of the pancreas.

T3

This means the cancer is bigger than 4cm but is still within the pancreas.

Diagram showing T3 cancer of the pancreas.

T4

This means the cancer has grown outside the pancreas, into the nearby large blood vessels.

Diagram showing T4 cancer of the pancreas.

Node (N)

Node (N) describes whether the cancer has spread to the lymph nodes.

  • N0 means there are no cancer cells in the nearby lymph nodes.

Diagram showing stage N0 of the pancreas.
  • N1 means that 1 to 3 nearby lymph nodes contain cancer cells.

Diagram showing stage N1 cancer of the pancreas.
  • N2 means that there is cancer in 4 or more nearby lymph nodes.

Diagram showing stage N2 cancer of the pancreas.

Unfortunately, if the cancer has spread to nearby lymph nodes there is a higher chance it may have spread further away from the pancreas.

Metastasis (M)

Metastasis (M) describes whether the cancer has spread to a different part of the body.

  • M0 means the cancer has not spread to other areas of the body.

  • M1 means the cancer has spread to other areas of the body such as the liver, lungs or lymph nodes further away from the pancreas.

Diagram showing M1 pancreatic cancer from the TNM staging system.

Treatment for pancreatic cancer

Knowing the cancer stage helps your doctor decide which treatment to recommend. Treatment also depends on:

  • where in the pancreas the cancer is

  • if your surgeon can remove (resect) the cancer

  • any treatment you have had already

  • your general health and level of fitness

The stage of the cancer and these other factors can also give your doctor an idea about your outlook (prognosis).

Last reviewed: 20 Aug 2026

Next review due: 20 Aug 2029

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