Transplant surgery for liver cancer
There are strict rules about who can have a liver transplant. You might be able to have a liver transplant if you have:
a single tumour no more than 5cm across
a single tumour that is 5 to 7cm across and has not grown for at least 6 months
no more than 5 small tumours, each no larger than 3cm across
a level of (AFP) less than 1000
Find more detailed information on who can have a transplant for liver cancer
You will need to travel to a specialist transplant centre to have your surgery.
To have a liver transplant your surgeon makes a large cut into the top part of tummy (abdomen). This often looks like a long curved line, a backwards L, or an upside down Y.
Your surgeon removes your liver and your . They cut the main blood vessels to your liver, as well as the . Sometimes your surgeon might use a machine to move blood back to your heart while the blood vessels are cut. This is called a bypass.
Once your liver has been removed, the new liver will be put in its place. The gallbladder from the new liver is removed. Your surgeon connects your blood vessels and bile duct to the ones in the new liver.
Your surgeon will usually put 2 drains in your tummy to collect any blood or . These will be removed a few days after your operation. They close your wound with clips or stitches.
After your liver transplant, you wake up in the . Your transplant team review you regularly and watch your progress closely. You usually move back to the ward after a few days.
Find out more about what happens after a liver transplant
There is a risk of problems or complications after a liver transplant. Some can happen straight after surgery when you're in hospital. Or you might have problems after you go home. Possible complications of a liver transplant include:
bleeding
kidney problems
infection
bile duct problems
rejection of the new liver
blood clots
depression or anxiety
Read more about the possible problems after a liver transplant
The NHS Blood and Transplant service have information about liver transplants. This includes details about waiting lists, how donors are matched, and the transplant procedure. Go to the NHS Blood and Transplant service website
We are designing new diagrams for this page. We will add them as soon as possible.
Last reviewed: 18 Feb 2025
Next review due: 18 Feb 2028
A liver transplant is an operation to remove your liver and replace it with a healthy liver from a donor.
Surgery is one of the main treatments for early cancer that started in the liver (primary liver cancer).
Your treatment for liver cancer depends on the stage of your cancer and how well your liver is working. The most common treatments are surgery, heat treatment, drug treatments and radiotherapy.
Liver cancer is a cancer that starts in the liver. You might hear it called primary liver cancer.
Primary liver cancer is cancer that started in the liver. This section is mainly about the most common type of liver cancer, hepatocellular carcinoma (HCC).

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