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Gestational trophoblastic disease (GTD)

Invasive mole and choriocarcinoma

Invasive mole, also called persistent trophoblastic disease, and choriocarcinoma are very rare types of cancer that can occur after pregnancy. They are types of gestational trophoblastic disease.

What is invasive mole and choriocarcinoma?

An invasive mole and choriocarcinoma are rare cancers. They grow from the tissue that forms in the womb during pregnancy.

Symptoms of invasive mole and choriocarcinoma

Some women may not have any symptoms. This is particularly the case for a woman with an invasive mole as these are usually picked up during follow up for a molar pregnancy.If there are symptoms, the main symptoms for an invasive mole or choriocarcinoma is vaginal bleeding.

Diagnosing invasive mole and choriocarcinoma

If you develop an invasive mole or choriocarcinoma it usually shows up on some tests before you notice any symptoms. Your specialist team will then ask you to go in to see them.

Tests and scans for invasive mole and choriocarcinoma

You might have a number of tests or scans to help diagnose or monitor an invasive mole or choriocarcinoma.

Survival for invasive mole and choriocarcinoma

Survival for invasive mole and choriocarcinoma is very high. Nearly all women are cured.

Treatment for invasive mole and choriocarcinoma

The main treatment for invasive mole or choriocarcinoma is chemotherapy. But some women might be offered surgery.

Last reviewed: 03 Oct 2025

Next review due: 03 Oct 2028

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