Mesothelioma incidence statistics

Cases

New cases of mesothelioma, 2015, UK

 

Proportion of all cases

Percentage mesothelioma is of total cancer cases, 2015, UK

 

Age

Peak rate of mesothelioma cases, 2013-2015, UK

Trend over time

Change in mesothelioma cancer incidence rates since the early 1990s, UK

Mesothelioma is not among the 20 most common cancers in the UK, accounting for less than 1% of all new cancer cases (2015).[1-4]

In males in the UK, mesothelioma is the 18th most common cancer (1% of all new male cancer cases). In females in the UK it is not among the 20 most common cancers (less than 1% of all new female cancer cases).

83% of mesothelioma cases in the UK are in males, and 17% are in females.

Mesothelioma incidence rates (European age-standardised (AS) rates Open a glossary item) for persons are significantly lower than the UK average in Northern Ireland, Scotland and Wales, and similar to the UK average in England.

Mesothelioma (C45), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2015

  England Scotland Wales Northern Ireland UK
Male Cases 1,952 160 97 41 2,250
Crude Rate 7.2 6.1 6.4 4.5 7.0
AS Rate 8.8 7.3 6.9 6.4 8.5
AS Rate - 95% LCI 8.4 6.1 5.6 4.5 8.2
AS Rate - 95% UCI 9.2 8.4 8.3 8.4 8.9
Female Cases 390 34 14 9 447
Crude Rate 1.4 1.2 0.9 1.0 1.4
AS Rate 1.5 1.2 0.8 1.1 1.4
AS Rate - 95% LCI 1.3 0.8 0.4 0.4 1.3
AS Rate - 95% UCI 1.6 1.6 1.2 1.8 1.5
Persons Cases 2,342 194 111 50 2,697
Crude Rate 4.3 3.6 3.6 2.7 4.1
AS Rate 4.8 3.8 3.5 3.3 4.6
AS Rate - 95% LCI 4.6 3.3 2.9 2.4 4.4
AS Rate - 95% UCI 5.0 4.4 4.2 4.3 4.7

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item  around the AS Rate Open a glossary item
 

For mesothelioma, like most cancer types, differences between countries largely reflect risk factor prevalence in years past.

References

  1. Data were provided by the Office for National Statistics on request, July 2017. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, August 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, October 2017. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, July 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2015, ICD-10 C45.

Last reviewed:

Mesothelioma incidence is strongly related to age, with the highest incidence rates being in older people. In the UK in 2013-2015, on average each year around half (51%) of new cases were in people aged 75 and over.[1-4

Age-specific incidence rates rise steeply in males and gradually in females from around age 50-54 and drop in the oldest age groups. The highest rates are in the 80 to 84 age group for males and the 75 to 79 age group for females.

Incidence rates are significantly higher in males than females in a number of (mainly older) age groups. The gap is widest at age 90+, when the age-specific incidence rate is 9.8 times higher in males than females.

Mesothelioma (C45), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Population, UK, 2013-2015

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate Open a glossary item
 

For mesothelioma, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors. A drop or plateau in incidence in the oldest age groups often indicates reduced diagnostic activity perhaps due to general ill health.

References

  1. Data were provided by the Office for National Statistics on request, July 2017. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, August 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, October 2017. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, July 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2013-2015, ICD-10 C45.

Last reviewed:

Mesothelioma European age-standardised (AS) Open a glossary item incidence rates for males and females combined increased by 67% in the UK between 1993-1995 and 2013-2015.[1-4] The increase was larger in females than in males.

For males, mesothelioma AS incidence rates in the UK increased by 58% between 1993-1995 and 2013-2015. For females, mesothelioma AS incidence rates in the UK increased by 96% between 1993-1995 and 2013-2015.

Over the last decade in the UK (between 2003-2005 and 2013-2015), mesothelioma AS incidence rates for males and females combined increased by 7%. In males AS incidence rates remained stable, and in females rates increased by 16%.

Mesothelioma (C45), European Age-Standardised Incidence Rates, UK, 1993-2015

Mesothelioma incidence rates have increased overall in some broad adult age groups in males and females combined in the UK since the early 1990s, but have decreased in others.[1-4] Rates in 25-49s have decreased by 74%, in 50-59s have decreased by 62%, in 60-69s have increased by 13%, in 70-79s have increased by 130%, and in 80+s have increased by 314%.

Mesothelioma (C45), European Age-Standardised Incidence Rates, By Age, UK, 1993-2015

For mesothelioma, like most cancer types, incidence trends largely reflect changing prevalence of risk factors and improvements in diagnosis and data recording. Recent incidence trends are influenced by risk factor prevalence in years past, and trends by age group reflect risk factor exposure in birth cohorts.

References

  1. Data were provided by the Office for National Statistics on request, July 2017. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, August 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, October 2017. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, July 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1993-2015, ICD-10 C45.

Last reviewed:

Most mesothelioma cases occur in the pleura Open a glossary item, with much smaller proportions in the peritoneum Open a glossary item and pericardium Open a glossary item (2010-2012).[1-4] This reflects that asbestos typically enters the body via inhalation, rather than ingestion.[5]

The proportion of cases in each part is similar between males and females.[1-4]

A small proportion of cases did not have the specific site of the mesothelioma recorded in cancer registry data, or overlapped more than one part.[1-4]

Cases and percentages may not sum due to rounding

References

  1. Data were provided by the Office for National Statistics on request, July 2014. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html.
  2. Data were provided by ISD Scotland on request, April 2014. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, April 2014. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.
  4. Data were provided by the Northern Ireland Cancer Registry on request, June 2014. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/CancerInformation/.
  5. Robinson BW, Musk AW, Lake RA. Malignant mesothelioma. Lancet 2005;366(9483):397-408.

About this data

Data is for UK, 2010-2012, ICD-10 C45.

Last reviewed:

Mesothelioma incidence rates are projected to fall by 53% in the UK between 2014 and 2035, to 3 cases per 100,000 people by 2035.[1] This includes a larger decrease for males than for females.

For males, mesothelioma European age-standardised (AS) Open a glossary item incidence rates in the UK are projected to fall by 55% between 2014 and 2035, to 5 cases per 100,000 by 2035.[1] For females, rates are projected to fall by 46% between 2014 and 2035, to 1 cases per 100,000 by 2035.[1]

Mesothelioma (C45), Observed and Projected Age-Standardised Incidence Rates, by Sex, UK, 1979-2035

 

It is projected that 2,116 cases of mesothelioma (1,753 in males, 363 in females) will be diagnosed in the UK in 2035.

References

  1. Smittenaar CR, Petersen KA, Stewart K, Moitt N. Cancer Incidence and Mortality Projections in the UK Until 2035. Brit J Cancer 2016.

About this data

Data is for: UK, 1979-2014 (observed), 2015-2035 (projected), ICD-10 C45

Projections are based on observed incidence and mortality rates and therefore implicitly include changes in cancer risk factors, diagnosis and treatment. It is not possible to assess the statistical significance of changes between 2014 (observed) and 2035 (projected) figures. Confidence intervals are not calculated for the projected figures. Projections are by their nature uncertain because unexpected events in future could change the trend. It is not sensible to calculate a boundary of uncertainty around these already uncertain point estimates. Changes are described as 'increase' or 'decrease' if there is any difference between the point estimates.

More on projections methodology

Last reviewed:

There is no evidence for an association between mesothelioma incidence and deprivation for either males or females in England.[1] England-wide data for 2006-2010 show European age-standardised Open a glossary item incidence rates are similar for both males and females living in the most deprived areas compared with the least deprived.[1]

Mesothelioma (C45), European Age-Standardised Incidence Rates by Deprivation Quintile, England, 2006-2010

The estimated deprivation gradient in mesothelioma incidence between people living in the most and least deprived areas in England has not changed in the period 1996-2010.[1]

References

  1. Cancer Research UK and National Cancer Intelligence Network. Cancer by deprivation in England: Incidence, 1996-2010, Mortality, 1997-2011. London: NCIN; 2014.

About this data

Data is for UK, 2006-2010, ICD-10 C45

Deprivation gradient statistics were calculated using incidence data for 2006-2010. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

Last reviewed:

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