Bone sarcoma incidence statistics

Cases

New cases of bone sarcoma, 2014-2016 average, UK

 

Proportion of all cases

Percentage bone sarcoma is of total cancer cases, 2014-2016 average, UK

 

Age

Peak rate of bone sarcoma cases, 2014-2016, UK

Trend over time

Bone sarcoma incidence rates have changed differently for each sex since the early 1990s, UK

 

Bone sarcoma is not among the 20 most common cancers in the UK, accounting for less than 1% of all new cancer cases (2016).[1-4]

In females in the UK it is not among the 20 most common cancers (less than 1% of all new female cancer cases). In males in the UK, bone sarcoma is not among the 20 most common cancers (less than 1% of all new male cancer cases).

46% of bone sarcoma cases in the UK are in females, and 54% are in males.

Bone sarcoma incidence rates (European age-standardised (AS) rates Open a glossary item) are similar to the UK average in all the UK constituent countries.

Bone Sarcoma (C40-C41), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2016​

  England Scotland Wales Northern Ireland UK
Female Cases 207 19 8 7 241
Crude Rate 0.7 0.7 0.5 0.7 0.7
AS Rate 0.8 0.7 0.5 0.8 0.7
AS Rate - 95% LCL 0.6 0.4 0.2 0.2 0.6
AS Rate - 95% UCL 0.9 1.0 0.8 1.4 0.8
Male Cases 233 29 13 3 278
Crude Rate 0.9 1.1 0.8 0.3 0.9
AS Rate 0.9 1.2 0.8 0.3 0.9
AS Rate - 95% LCL 0.8 0.7 0.4 0.0 0.8
AS Rate - 95% UCL 1.0 1.6 1.3 0.6 1.0
Persons Cases 440 48 21 10 519
Crude Rate 0.8 0.9 0.7 0.5 0.8
AS Rate 0.8 0.9 0.7 0.6 0.8
AS Rate - 95% LCL 0.7 0.7 0.4 0.2 0.7
AS Rate - 95% UCL 0.9 1.2 1.0 1.0 0.9

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item  around the AS Rate Open a glossary item 

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, August 2018. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2018. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, February 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, April 2018. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/

About this data

Data is for UK, 2016, ICD-10 C40-C41.

Last reviewed:

Bone sarcoma incidence is related to age, with the highest incidence rates being in older people. In the UK in 2014-2016, on average each year almost 3 in 20 (13%) new cases were in people aged 75 and over.[1-4]

Age-specific incidence rates rise steadily from birth to around age 10-19 and drop until around age 40-44, then rise steadily again until around age 75-79 when the rise becomes steeper in males. The highest rates are in the 90+ age group for females and males.

Incidence rates are similar between females and males in most age groups.

Bone Sarcoma (C40-C41), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Population, UK, 2014-2016

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item  around the AS Rate Open a glossary item
 

For bone sarcoma, like most cancer types, incidence increases with age. This largely reflects cell DNA damage accumulating over time. Damage can result from biological processes or from exposure to risk factors. A drop or plateau in incidence in the oldest age groups often indicates reduced diagnostic activity perhaps due to general ill health.

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, August 2018. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2018. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, February 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, April 2018. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2014-2016, ICD-10 C40-C41.

Last reviewed:

Bone sarcoma European age-standardised (AS) Open a glossary item incidence rates for females and males combined remained stable in the UK between 1993-1995 and 2014-2016.[1-4] The change varied markedly between sexes.

For females, bone sarcoma AS incidence rates in the UK increased by 18% between 1993-1995 and 2014-2016. For males, bone sarcoma AS incidence rates in the UK remained stable between 1993-1995 and 2014-2016.

Over the last decade in the UK (between 2004-2006 and 2014-2016), bone sarcoma AS incidence rates for females and males combined remained stable. In females AS incidence rates remained stable, and in males rates remained stable.

Bone Sarcoma (ICD-10 C40-C41), European Age-Standardised Incidence Rates, UK, 1993-2016

Bone sarcoma incidence rates have remained stable overall in some broad age groups in females and males combined in the UK since the early 1990s, but have increased in others.[1-4] Rates in 0-24s have remained stable, in 25-49s have increased by 34%, in 50-59s have increased by 53%, in 60-69s have remained stable, in 70-79s have remained stable, and in 80+s have remained stable.

Bone Sarcoma (ICD-10 C40-C41), European Age-Standardised Incidence Rates, By Age, UK, 1993-2016

References

  1. Data were provided by the National Cancer Registration and Analysis Service (part of Public Health England), on request through the Office for Data Release, August 2018. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases
  2. Data were provided by ISD Scotland on request, April 2018. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, February 2019. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, April 2018. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/

About this data

Data is for UK, 1993-2016, ICD-10 C40-C41.

Last reviewed:

The largest proportion of bone sarcoma cases occur in the lower limb, with smaller proportions in the pelvic bones, and much smaller proportions in the upper limb and head (2010-2012).[1-4]

The proportion of cases in each part of the body is similar between males and females.[1-4]

A moderate proportion of cases did not have the specific location of the sarcoma recorded in cancer registry data, or overlapped more than one part.[1-4]

Cases and percentages may not sum due to rounding

References

  1. Data were provided by the Office for National Statistics on request, July 2014. Similar data can be found here:http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html.
  2. Data were provided by ISD Scotland on request, April 2014. Similar data can be found here:http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, April 2014. Similar data can be found here:http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.
  4. Data were provided by the Northern Ireland Cancer Registry on request, June 2014. Similar data can be found here:http://www.qub.ac.uk/research-centres/nicr/CancerInformation/.

About this data

Data is for UK, 2010-2012, ICD-10 C41-C42.

Last reviewed:

Bone sarcoma incidence rates are projected to fall by 5% in the UK between 2014 and 2035, to 1 case per 100,000 people by 2035.[1] This includes an increase for females and a drop for males.

For males, bone sarcoma European age-standardised (AS) Open a glossary item incidence rates in the UK are projected to fall by 31% between 2014 and 2035, to 1 case per 100,000 by 2035.[1] For females, rates are projected to rise by 24% between 2014 and 2035, to 1 case per 100,000 by 2035.[1]

Bone sarcoma (C40-C41), Observed and Projected Age-Standardised Incidence Rates, by Sex, UK, 1979-2035

 

It is projected that 568 cases of bone sarcoma (217 in males, 351 in females) will be diagnosed in the UK in 2035.

References

  1. Smittenaar CR, Petersen KA, Stewart K, Moitt N. Cancer Incidence and Mortality Projections in the UK Until 2035. Brit J Cancer 2016.

About this data

Data is for: UK, 1979-2014 (observed), 2015-2035 (projected), ICD-10 C40-C41

Projections are based on observed incidence and mortality rates and therefore implicitly include changes in cancer risk factors, diagnosis and treatment. It is not possible to assess the statistical significance of changes between 2014 (observed) and 2035 (projected) figures. Confidence intervals are not calculated for the projected figures. Projections are by their nature uncertain because unexpected events in future could change the trend. It is not sensible to calculate a boundary of uncertainty around these already uncertain point estimates. Changes are described as"increase" or "decrease" if there is any difference between the point estimates.

More on projections methodology

Last reviewed:

There is no evidence for an association between bone sarcoma incidence and deprivation for either males or females in England.[1] England-wide data for 2006-2010 show European age standardised Open a glossary item incidence rates are similar for both males and females living in the most deprived areas compared with the least deprived.[1]

Bone Sarcoma (C40-C41), European Age-Standardised Incidence Rates by Deprivation Quintile, England, 2006-2010

The estimated deprivation gradient in bone sarcoma incidence between people living in the most and least deprived areas in England has not changed in the period 1996-2010.[1]

References

  1. Cancer Research UK and National Cancer Intelligence Network. Cancer by deprivation in England: Incidence, 1996-2010, Mortality, 1997-2011. London: NCIN; 2014.

About this data

Data is for UK, 2006-2010, ICD-10 C40-C41

Deprivation gradient statistics were calculated using incidence data for 2006-2010. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

Last reviewed:

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