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Clinical research statement of intent

Our research strategy shapes how we'll discover more about how cancer develops and progresses to unlock new and better ways to prevent, detect and treat it. Our clinical research statement of intent provides an overview of how we implement the research strategy and helps to guide the funding decisions made by our Clinical Research Committee. 

Read on or download the clinical research statement of intent as a PDF to learn more. You can also explore our research strategy to learn more about our overarching research priorities. 

Clinical research statement of intent (PDF, 389KB)Read our overarching research strategy

Our approach

As part of delivering our research strategy, we’re supporting high-quality clinical research focused on studying people, their tissues and data. This will deepen our understanding of cancer biology so we can translate that knowledge into better ways to prevent, detect, and treat it.

Our clinical research portfolio includes interventional clinical trials, observational studies and translational research that uses human tissues and data to develop model systems to study disease mechanisms. 

Clinician scientists are vital to our success, bridging the gap between discovery science and patient research. We encourage the inclusion of early career researchers at all stages of our funding scheme to support a pipeline of excellent scientists to lead future studies.

Explore our clinical research funding scheme

Our statement of intent

Deliver better outcomes through targeted, impactful clinical trials

We will build a portfolio of clinical research that: 

  • addresses critical clinical challenges 

  • deepens our understanding of cancer biology to inform more effective and kinder interventions  

  • has a particular focus on early-phase proof of concept trials and trials that optimise treatments and minimise adverse effects

Explore the clinical and translational projects we fund

Connect our clinical research community

To catalyse our work in this area, we will build a connected, collaborative and diverse research community by:  

  • increasing support for the brightest and best clinicians to train in outstanding research environments, such as our institutes

  • increasing opportunity and diversity in clinical research participation and workforce

  • building and nurturing effective partnerships

Read the full clinical research statement of intent(PDF, 389 KB)

Delivering our clinical research statement of intent

Our ambition is to build a research portfolio that addresses key clinical challenges and advances our understanding of cancer and its treatment to drive progress for patients.

Researcher studying samples on the screen.

Advance our biological understanding of cancer

We will build a portfolio that not only evaluates treatments, but also deepens our knowledge of cancer biology and how we treat it. 

We will address key clinical challenges and catalyse collaborations between discovery researchers, clinical scientists and trialists. 

We will promote innovation in trial methodology and maximise the value of data and samples by making them available for experimental medicine research and model systems. 

Researchers engaged in group discussion.

Support high-quality clinical trials

We will build a broad portfolio of clinical trials, with an increased focus on early-phase, proof-of-concept trials and experimental medicine studies that link clinical trial data and samples with research that deepens our understanding of cancer development and treatment response.  

We will support studies that improve or repurpose treatments that currently exist.

Researchers at their break.

Work in partnership to drive progress for patients

We will establish and strengthen partnerships to benefit patients. We will expect and promote excellence in patient and public involvement and engagement (PPIE) across our research.  

We will encourage research that considers PPIE and reduces barriers for underserved populations and explores the impact of disparities on cancer treatment.  

We will collaborate with the government, the NHS, and partners in the science sectors to shape the clinical research landscape and optimise trial setup and delivery. 

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