Discovery Research Committee awards

Discovery Programme Awards

November 2025

Therapeutic targeting of cancer stem cells in acute myeloid leukaemia

Professor Kamil Kranc

Institute of Cancer Research

Automated high precision AI-accelerated radiotherapy

Professor Uwe Oelfke

Institute of Cancer Research

Professor Anna Kirby

Royal Marsden NHS Foundation Trust and Institute of Cancer Research

Exploiting the cell cycle vulnerability landscape in ovarian cancer

Professor Stephen Taylor

University of Manchester

Understanding the immunologic and structural basis of antigen-specific tumour-directed human alloreactive immune T cell responses for therapeutic benefit

Professor Paresh Vyas

University of Oxford

Cellular enlargement as a driver of therapy-induced senescence and genome instability

Professor Adrian Saurin

University of Dundee

May 2025

Optimisation of anti-cancer CD4+ T cell responses through molecularly-informed modification of HLA class II antigens

Professor Andrew Godkin

Cardiff University

Professor Awen Gallimore

Cardiff University

Molecular mechanisms of the β-catenin destruction complex in normal signalling and cancer

Professor Sebastian Guettler

Institute of Cancer Research

G-quadruplex DNA mechanisms and cancer

Professor Sir Shankar Balasubramanian

University of Cambridge

Enhancing immune surveillance and targeting senescence to treat high-grade serous ovarian carcinoma

Professor Jesus Gil

Imperial College London

Defining mechanisms of T cell dysfunction in liver metastases of colorectal cancer

Professor Leonard Seymour

University of Oxford

Dr Kerry Fisher

University of Oxford

Dr Alex Gordon-Weeks

University of Oxford

Explore the Discovery Programme Award

Discovery Programme Foundation Awards

November 2025

Targeting the evolution of drug resistance in high grade serous ovarian cancer

Professor Michelle Lockley

Queen Mary University of London

Enabling immune destruction of tumours through precision targeting of extracellular matrix

Dr Oliver Pearce

Queen Mary University of London

June 2025

Application of a molecular and cellular imaging toolbox to develop and interrogate receptor-targeted cancer treatments

Dr Michelle Ma

King's College London

Leveraging RNA splicing inhibition to enhance efficacy of immunotherapies in immune-cold colorectal cancer

Dr Kevin Myant

University of Edinburgh

Tissue specificity of cell cycle dysregulation in cancer

Dr Alexis Barr

Imperial College London

Stem cell signatures of mutational order in colorectal cancer

Professor Simon Buczacki

University of Oxford

Explore the Discovery Programme Foundation Award

Multidisciplinary Project Awards

This funding scheme is now closed.

June 2025

Investigating cell plasticity via spatiotemporal epigenetic perturbation

Dr Marco Di Antonio

Imperial College London

Professor Luca Magnani

Institute of Cancer Research