Clinical Research Committee awards

Update to clinical schemes

Please note that all clinical funding schemes have been replaced with a single, modular scheme supporting clinical trials, experimental medicine and sample collection. Awards from 2025 onward reflect this change.

Clinical Research Funding Scheme

May 2025

ENHANCE: evaluating hormone therapy to achieve optimal doses in metastatic prostate cancer (Clinical Trial and Sample Collection module)

Professor Ananya Choudhury

University of Manchester

SERUM: defining MRD in CR by QIP-MS in blood in the myeloma XV RADAR trial - a blood-based biomarker to enhance patient care (Experimental Medicine module)

Dr I-Jun Lau

University of Oxford

Dr Ross Sadler

Oxford University Hospitals NHS

Sample collection for UK-MRA myeloma XVIII iFIT: immunotherapy approaches adapted for fitness in newly diagnosed transplant ineligible patients with myeloma (Sample Collection module)

Dr Charlotte Pawlyn

Institute of Cancer Research

Professor Gordon Cook

University of Leeds

Clinical Trial Award Endorsement

November 2024

RAdICAL - risk-adapted immunochemotherapy to cure aggressive lymphoma

Professor Christopher Fox

University of Nottingham

SALVOVAR trial: A pragmatic randomized phase III trial to assess the utility of adjusting chemotherapy dose & dosing schedule with the SALVage weekly dose-dense regimen in patients with poor prognostic OVARian cancers based on the tumour primary chemosensitivity and incomplete debulking surgery

Dr Andrew Clamp

University College London

Biomarker Project Awards

This funding scheme is now closed.

November 2024

Evaluation and refinement of a multigene prognostic signature and digital histology AI features for the prediction of metastasis in cutaneous squamous cell carcinoma

Dr Jun Wang

Queen Mary University of London

Pro-tumourigenic inflammation as a predictor of relapse post-surgery in early-stage non-small cell lung cancer

Dr Santiago Zelenay

Cancer Research UK Manchester Institute

Professor Caroline Dive

Cancer Research UK Manchester Institute

Prospective Sample Collection Awards

This funding scheme is now closed.

November 2024

Augmenting radiotherapy in rectal cancer to minimise invasive surgery (ARTEMIS) sample collection

Professor Simon Gollins

University of Leeds

Professor David Sebag-Montefiore

University of Leeds

Dr Mark Saunders

University of Leeds

Sample collection in early preoperative intervention studies in glioblastoma: POBIG and PORTRAIT

Dr Claire O’Leary

University of Manchester

Clinical Trial Awards

This funding scheme is now closed.

November 2024

CONNECT2007: Phase I/II study of lutathera in patients with recurrent and/or progressive high-grade central nervous system tumours and meningiomas that demonstrate uptake on DOTATATE PET

Dr Jenny Gains

University College London

Professor Darren Hargrave

University College London

A phase II/III trial evaluating use of circulating serum miRNA as part of active surveillance for patients with stage I seminoma and dysgerminoma (OTIS-S)

Professor Robert Huddart

The Institute of Cancer Research

Dr Alison Reid

The Institute of Cancer Research

Dr Fay Cafferty

The Institute of Cancer Research

Experimental Medicine Awards

This funding scheme is now closed.

November 2024

BIOINFORM: Biologically informed treatment decisions in acute leukaemia

Professor Anthony Moorman

Newcastle University