Hairy cell leukaemia
You might pick up infections more easily as the numbers of abnormal white blood cells rise. This is because abnormal white blood cells are not as good at fighting infection as healthy ones.
You might have very high temperatures if you have an uncontrolled infection.
You might feel tired and short of breath if you have a low level of (anaemia). This could happen if your bone marrow becomes crowded by abnormal white blood cells. So your bone marrow can’t produce enough red blood cells. Red blood cells help to carry oxygen around the body.
The extra white blood cells take up more space in the bone marrow as their numbers rise. So there's not enough room for the bone marrow to make platelets. Platelets normally help the blood to clot, so you might have:
nosebleeds
unexplained bruising
unusually heavy periods
The spleen is an organ on the left of your body, just under your ribs. It is part of the lymphatic system. Hairy cell leukaemia can cause your spleen to be bigger than normal. This is called an enlarged spleen.
Your doctor might be able to feel your enlarged spleen. Your abdomen might be uncomfortable or painful.
Leukaemia cells building up in the liver can also cause tummy (abdominal) swelling.
Hairy cell leukaemia itself uses up energy that your body would otherwise use or store. So you might lose weight, even if you're eating normally.
An enlarged spleen may also contribute to weight loss by squashing your stomach. This can make you feel full more quickly than usual, so you eat less than you normally would.
Last reviewed: 24 Sept 2024
Next review due: 24 Sept 2027
You usually start by seeing your GP and they might refer you to a specialist and organise tests. Find out more about tests and screening for hairy cell leukaemia.
The stage means how far your leukaemia has developed. There is no widely agreed staging system for hairy cell leukaemia.
There are different treatments for hairy cell leukaemia. You might have one treatment, or a combination. The main treatment is chemotherapy.
Hairy cell leukaemia (HCL) is a rare type of chronic leukaemia. It develops slowly from white cells called B lymphocytes.
Hairy cell leukaemia (HCL) is a rare type of chronic leukaemia. It develops slowly from white blood cells called B lymphocytes. Find out about this type of leukaemia.

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