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Stages, types and grades

Stage 2 bowel cancer

Stage 2 bowel cancer means it has spread into the outer wall of the bowel or into tissue or organs next to the bowel. It has not spread anywhere else. There are a number of treatment options.

About stage 2 bowel cancer

Stage 2 bowel (colon and rectal) cancer has spread into the outer wall of the bowel or into tissue or organs next to the bowel. It has not spread to the lymph nodes or distant parts of the body.

Stage 2 is divided into 3 stages - 2A, 2B and 2C.

Stage 2A

Stage 2A means that the cancer has grown into the outer lining of the bowel. 

Diagram showing Stage 2A bowel cancer.

Stage 2B

Stage 2B means that the cancer has grown through the outer lining of the bowel into the tissue layer (peritoneum) covering the organs in the tummy (abdomen).

Diagram showing Stage 2B bowel cancer.

Stage 2C

Stage 2C means that the cancer has grown through the wall of the colon or rectum, into organs and tissues next to it.

Diagram showing Stage 2C bowel cancer.

TNM stages

The TNM staging system stands for Tumour, Node, Metastasis.

In the TNM staging system, stage 2A bowel cancer is the same as:

  • T3, N0, M0.

Stage 2B is the same as:

  • T4a, N0, M0. 

Stage 2C bowel cancer is the same as:

  • T4b, N0, M0.

Find out about the TNM system

Treatment for stage 2 large bowel (colon) cancer

You have surgery to remove your cancer.

Your surgeon might suggest ​​ before or after surgery.

Chemotherapy before surgery can shrink the cancer to make it easier for to remove. Chemotherapy after surgery can lower the chance of your cancer coming back after surgery.

Read more about treatment for colon cancer

Treatment for stage 2 rectal cancer of the back passage (rectal cancer)

The main treatments are:

  • surgery

  • chemotherapy

  • chemotherapy combined with radiotherapy (chemoradiotherapy)

You might have:

  • surgery as your only treatment

  • a short course of radiotherapy, followed by surgery

  • a course of chemoradiotherapy, followed by surgery

  • a course of chemotherapy, followed by surgery

  • total neoadjuvant therapy (TNT) – this might be chemoradiotherapy and a course of chemotherapy all before surgery

Further treatment

Rarely, your doctor might offer you chemotherapy after surgery, especially if you haven’t had this before surgery.

Read more about treatment for rectal cancer

Other stages

Last reviewed: 08 Jan 2025

Next review due: 08 Jan 2028

Stages and grades of bowel cancer

The stage of a cancer tells you how far it has grown through the bowel wall and whether it has spread to nearby lymph nodes or other organs. It helps your doctor to know which treatment you need.

Treatment for bowel cancer

Treatment depends on whether you have colon or rectal cancer, as well as your cancer stage. You might have surgery, radiotherapy or chemotherapy or a combination of these.

Living with bowel cancer

Living with bowel (colorectal) cancer may mean you have changes to your diet, sex life or body image. There is support to help you cope.

Bowel (colorectal) cancer main page

Bowel cancer means cancer that starts in the colon (large bowel) or back passage (rectum). It is also known as colorectal cancer.

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