“I think it’s really important that people keep signing up to these type of trials to push research forward.”
A study collecting samples to help doctors learn more about cancer and other illnesses
This study is looking at tissue, blood, urine and a type of fluid that can build up in your body called ascitic fluid to understand how the human body works normally, and what changes when things go wrong.
In Leeds, many people are carrying out research into a range of illnesses, including cancer. Each team has different reasons for their research, but they are mainly to try and understand more about what has changed in these diseases and why.
Changes in proteins, genes or other substances the researchers find may be markers for the particular disease they are investigating (
Samples from healthy volunteers and people with minor or major illnesses are important to researchers, as they need to compare them and see what is normal and what changes in different diseases. In this study, the team will ask permission to collect spare tissue from surgery, and also blood, urine and ascitic fluid from people already giving these as part of routine treatment. Healthy volunteers will also be able to give blood samples. Samples will be stored in the ‘Leeds Multidisciplinary Research Tissue Bank’.
Who can enter
Researchers in Leeds hope in future to get permission for a wider group of people to give samples. At the moment, you can take part in this study if you are in Leeds and are in one of the following situations
- You have kidney cancer, prostate cancer, bladder cancer, bowel cancer or a brain tumour
- You have ovarian cancer, or are having surgery to remove your ovaries (a
bilateral oophorectomy) to reduce your risk of ovarian cancer
- You have any other kidney or
urinary tractdisease that is not cancer, for example repeated urine infections, kidney stones or kidney failure
- You do not have cancer, but are due to have surgery for another condition
- You do not have any health problems, but would like to take part in the study (you are a healthy volunteer)
You cannot enter this study if
- For any reason you are not able to understand what the study involves and give permission (consent) for samples to be used
- You are being cared for in prison
- You have an infectious disease such as HIV, Hepatitis B or Hepatitis C, or are thought to be at high risk for these diseases
- You are under 18 years of age
Everyone taking part in the study will give one or more samples, depending on their situation. You will also give permission for the team to look at information from your medical records that would help them in this research. They will treat this information anonymously, so no one can link it to you.
If you are having surgery, the team will ask permission to store and study any tissue removed during your surgery that your medical team do not need to keep.
The team will also ask if you would be willing to give one or more blood samples. How many you give depends on your situation, and the team will tell you more about this. You may also be asked to give a urine sample.
The team may ask if you would be willing to give further samples during future hospital visits. They will explain how they will use any samples you give.
Samples may be used in studies looking at
Where possible, you will give samples when you are already at the hospital. If you are a healthy volunteer and not due to have any blood tests, you will need to make an extra hospital visit to take part.
You should not have any side effects from taking part in this study.
It is possible that some of the information the team discover may show changes that could be relevant to other illnesses. For example, they may find that you are at risk of an illness determined by the
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Rosamonde Banks
Brain Tumour Research and Support across Yorkshire (BTRS)
Cancer Research UK
Department of Health
The PPR Foundation