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The Rest is Science podcast presenters.

The Rest Is Science

We've partnered with Goalhanger, Europe's largest independent podcast producer, on a new series where curiosity meets discovery.

About the series

The Rest Is Science podcast brings together mathematician and best-selling author Professor Hannah Fry and YouTuber Michael Stevens (aka VSauce) to explore the wonders of science. From groundbreaking discoveries to age-old scientific mysteries, the duo dives into topics that challenge our understanding of the world.

Discover the podcast

Watch all episodes on YouTube

More ways to listen

Listen on Apple podcasts Listen on Spotify

Cancer breakthroughs

One of the most complex topics they’ll discuss is cancer – a disease with more than 200 distinct types that present unique challenges.

Over the past 50 years, our pioneering work has helped double cancer survival in the UK. With our help, The Rest Is Science explores some of the breakthroughs that are driving a revolution in our understanding of cancer and our ability to beat it.

Redefining how cancer begins

For decades, the textbook theory was that cancer starts when our DNA gets damaged. But thanks to Cancer Grand Challenges, a research initiative we co-founded with the US National Cancer Institute, we now know that this damage alone isn’t always enough. A global team, called Team Mutographs, discovered cancer causes that don’t damage DNA. This has fundamentally changed our understanding of how cancer starts and could lead to new ways to prevent it. Discover the science

A close up photograph of DNA.

Stopping cancer before it starts

Our scientists proved that nearly all cervical cancers are caused by HPV (human papillomavirus), which led to the HPV vaccine. Now, the HPV vaccine is expected to prevent almost 90% of cervical cancers in the UK. And a world where almost no one will develop the disease is no longer a dream, but a real possibility. Read more on Cancer News

Cervical cancer cells close up.

Discovering cancer-causing genes

The BRCA genes help repair cells and keep them healthy. But when they’re faulty, these genes can increase the risk of certain cancers. Our scientists discovered BRCA2 and helped discover BRCA1, which has led to new treatments for BRCA-driven cancers. It also means that we can spot these cancers earlier and even stop some of them from developing at all. Read more about BRCA genes

A group of researchers working in the lab.

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