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Past research into bladder cancer

Our milestones

Our scientists have made vital contributions to finding new and better ways to treat, diagnose and prevent bladder cancer. Below are a few of our most important discoveries.

Understanding disease biology

2004  – We highlight a potential marker for aggressive disease, showing that high levels of a gene called E2F3 could flag cancers that need more urgent treatment. This may allow doctors to diagnose the disease more accurately in the future and choose treatments that are best for patients.

Improving diagnosis

1998 – Our scientists pioneer a new technique that leads to the development of urine tests that could spot bladder cancer earlier and make diagnosing the disease less uncomfortable than the current test (cystoscopy). The new technology is now being tested in clinical trials.

Radiotherapy and chemotherapy

1972 – We play a crucial role in the development of cisplatin, an important chemotherapy drug for bladder cancer that has spread. Our lab research shows the strong anti-cancer activity of the drug, prompting further research and clinical trials that we funded showing how effective it is for patients with certain types of cancer.

2008 – Our scientists show that radiotherapy is an effective option for people with bladder cancer who aren’t well enough or opt not to have surgery. Then in 2012 we fund a large trial which shows that adding low doses of chemotherapy to the radiotherapy option means patients with aggressive bladder cancer were 50% less likely to see their disease come back.  

A close up of a dropping sample on a microscope slide.

Current research

From studying the biology of bladder cancer cells in the lab to leading clinical trials testing cutting-edge treatments, our researchers are working hard to ensure more people survive bladder cancer.

Find out more about our current research

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Patients' stories

Meet people like Tommy who have experienced first-hand how our research is making a difference. The life-saving research we do wouldn’t be possible without your support.

Read stories from bladder cancer patients

Further information

Want to find more information about our research or bladder cancer?

Find out more about clinical trials

More about the symptoms and treatments for bladder cancer